GDF15 Monoclonal Antibody

Datasheet
Code CSB-MA999881A0m
Product Type Monoclonal Antibody
Size US$350Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q99988
Image
  • Immunohistochemistry of paraffin-embedded human adrenal gland using CSB-MA999881A0m in 30μg/ml dilute concentrations.

Immunogen Recombinant GDF15 Protein
Raised in mouse
Species Reactivity Human
Specificity specific for Human GDF15 denatured and native forms
Tested Applications ELISA,IHC;Recommended dilution:IHC:1:50-1:500
Relevance Growth differentiation factor 15 (GDF15) is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes.[1] GDF15 is also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB.[2] GDF15 mRNA is most abundant in the liver, with lower levels seen in some other tissues. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung.
Form liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300 Constituents: 0.01M PBS, PH 7.4
Purification Method >95%,Protein G purified
Isotype IgG2a
Clonality monoclonal
Alias Growth/differentiation factor 15, GDF-15, MIC1, PDF, PLAB, PTGFB
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Gene Names GDF15
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Clone No. 5E1A5
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Subcellular Location Secreted
Protein Families TGF-beta family
Tissue Specificity Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney (PubMed:9348093). Detected in plasma (at protein level) (PubMed:28572090, PubMed:29046435).
Database Links

HGNC: 30142

OMIM: 605312

KEGG: hsa:9518

STRING: 9606.ENSP00000252809

UniGene: Hs.616962

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