GDF15, a member of the TGFβ superfamily and also known as MIC-1 and PDF, functions as a stress response protein with key roles in various disease pathways. By binding to GFRAL-RET receptors, GDF15 regulates physiological processes including appetite, body weight, insulin sensitivity, and inflammatory responses. Its elevated levels in tumors, cardiovascular, and metabolic diseases position it as a potential biomarker and a novel target for therapeutic development. GDF15-targeted therapies are emerging as a cutting-edge area of research, aiming to offer innovative treatment strategies by modulating GDF15 expression levels.
Recombinant Human Growth/differentiation factor 15 (GDF15), partial (CSB-EP859530HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
GDF15 Recombinant Monoclonal Antibody (CSB-RA285852A0HU)
Validated Data
IHC image of CSB-RA285852A0HU diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
The following GDF15 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
GDF15 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA10029B0Rb | GDF15 Antibody, HRP conjugated | Human | ELISA |
CSB-PA10029D0Rb | GDF15 Antibody, Biotin conjugated | Human | ELISA |
CSB-PA10029A0Rb | GDF15 Antibody | Human | ELISA, WB, IHC |
CSB-PA563663 | GDF15 Antibody | Human | ELISA,WB |
CSB-PA002673 | GDF15 Antibody | Human | WB, ELISA |
CSB-MA999881A0m | GDF15 Monoclonal Antibody | Human | ELISA,IHC |
CSB-PA779597 | GDF15 Antibody | Human,Mouse | ELISA,WB |
CSB-PA255283 | GDF15 Antibody | Human | ELISA,IHC |
CSB-RA285852A0HU | GDF15 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
CSB-RA859530MA1HU | GDF15 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
GDF15 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-EP859530HU | Recombinant Human Growth/differentiation factor 15 (GDF15), partial | E.coli |
CSB-YP859530HU CSB-BP859530HU CSB-MP859530HU CSB-EP859530HU-B |
Recombinant Human Growth/differentiation factor 15 (GDF15), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP859530HU1 | Recombinant Human Growth/differentiation factor 15 (GDF15), partial | E.coli |
GDF15 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E12009h | Human growth differentiation factor 15(GDF15)ELISA Kit | serum, plasma, tissue homogenates, urine | 1.95 pg/mL |
GDF15 ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL009345MO | Mouse Growth/differentiation factor 15(GDF15) ELISA kit | serum, plasma, tissue homogenates | 1.95 pg/ml |
GDF15 ELISA Kit for Rattus norvegicus (Rat)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E16317r | Rat growth differentiation factor 15(GDF15)ELISA Kit | serum, plasma, tissue homogenates | 0.39 pg/mL |