CD19 (Ab-531) Antibody

Datasheet
Code CSB-PA253616
Product Type Polyclonal Antibody
Size US$297
Uniprot No. P15391
Image
  • Western blot analysis of extracts from COS7 cells, treated with Serum (10%, 30mins), using CD19 (Ab-531) antibody.
Immunogen Synthesized non-phosphopeptide derived from Human CD19 around the phosphorylation site of tyrosine 531 (D-S-Y(p)-E-N).
Raised in Rabbit
Species Reactivity Human,Mouse
Specificity The antibody detects endogenous levels of total CD19 protein.
Tested Applications ELISA,WB;WB:1:500-1:3000
Relevance Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

Manabu Fujimoto, J. Biol. Chem., Nov 2001; 276: 44820 - 44827.
LE Bradbury, J. Immunol., Sep 1993; 151: 2915.
Minoru Hasegawa, J. Immunol., Sep 2001; 167: 2469.
Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality Polyclonal
Alias B-lymphocyte surface antigen B4; CD19; Leu-12;
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Target Names CD19
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Involvement in disease Immunodeficiency, common variable, 3 (CVID3)
Subcellular Location Membrane, Single-pass type I membrane protein
Database Links

HGNC: 1633

OMIM: 107265

KEGG: hsa:930

STRING: 9606.ENSP00000437940

UniGene: Hs.652262

Pathway PI3K-Akt signaling pathway
B cell receptor signaling pathway
Hematopoietic cell lineage

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