IL1B Antibody

Datasheet
Code CSB-PA003023
Size US$167
Image
  • Western Blot analysis of HeLa cells using IL-1β Polyclonal Antibody
  • Western Blot analysis of L929 MOUSE-BRAIN cells using IL-1β Polyclonal Antibody

Product Details

Uniprot No. P01584
Target Names IL1B
Alternative Names IL1B; IL1F2; Interleukin-1 beta; IL-1 beta; Catabolin
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the Internal region of Human IL-1β.
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Isotype IgG
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form Liquid
Tested Applications WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
Protocols Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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Citations

Imipenem toxicity in male reproductive organs as a result of inflammatory microenvironment and oxidative stress in germinal cells. Cherif B, et al,Toxicology,2019

Sample type: Testis tiusse
Sample species: Human
Application: IHC
Review: Bax, Bcl-2 and IL-1 beta expression analysis by immunohistochemical staining in testis of rat. Control; IM15, IM50 and IM100: groups treated with imipenem/cilastatin at respectively 15, 50
and 100 mg/kg; GM group treated with 50 mg/kg of gentamicin.
PMID: 30721722

Early Pattern of Epstein-Barr Virus Infection in Gastric Epithelial Cells by “Cell-in-cell”. Yue W, et al,Virologica Sinica,2019

Applications: WB
Review: The protein expression of IL-1b at the indicated time points post-infection.
PMID: 30911896

Target Data

Function Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells.
Subcellular Location Cytoplasm, cytosol, Lysosome, Secreted, exosome, Secreted
Protein Families IL-1 family
Tissue Specificity Expressed in activated monocytes/macrophages (at protein level).
Database Links

HGNC: 5992

OMIM: 147720

KEGG: hsa:3553

STRING: 9606.ENSP00000263341

UniGene: Hs.126256

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