PDCD1 Antibody

Datasheet
Code CSB-PA619964LA01HU
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Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q15116
Image
  • Western blot
    All lanes: PDCD1 antibody at 6µg/ml
    Lane 1: 293T whole cell lysate
    Lane 2: Hela whole cell lysate
    Lane 3: K562 whole cell lysate
    Lane 4: Mouse stomach tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 32 kDa
    Observed band size: 32 kDa

  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA619964LA01HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA619964LA01HU at dilution of 1: 100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Immunogen Recombinant Human Programmed cell death protein 1 protein (21-170AA)
Raised in Rabbit
Species Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200
Relevance Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279), PDCD1, PD1
Immunogen Species Human
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Research Area Cell Biology
Target Names PDCD1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors.
Involvement in disease Systemic lupus erythematosus 2 (SLEB2)
Subcellular Location Membrane, Single-pass type I membrane protein
Database Links

HGNC: 8760

OMIM: 109100

KEGG: hsa:5133

STRING: 9606.ENSP00000335062

UniGene: Hs.158297

Pathway T cell receptor signaling pathway

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