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The recombinant monoclonal antibody targeting ERBB2 is produced through a series of steps. Initially, ERBB2 antibody genes are integrated into plasmid vectors. These modified plasmid vectors are then introduced into suitable host cells for expression using exogenous protein expression techniques. Subsequently, the ERBB2 recombinant monoclonal antibody is purified using affinity chromatography. Comprehensive validation of this antibody has been conducted for specific applications, including ELISA and IHC. It's important to emphasize that this antibody exclusively recognizes the human ERBB2 protein.
The main function of ERBB2 (HER2) is to regulate cell signaling pathways that control cell growth, proliferation, differentiation, and survival. Dysregulation of ERBB2 signaling is associated with cancer development and progression.
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