Code | CSB-MP007763HU |
Size | $228 |
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CUSABIO expressed the human ERBB2 amino acid residues Met23-Thr652 carrying a C-terminal 6xHis-tag in the mammalian cells. The obtained product is the recombinant partial-length human ERBB2 protein. The purity of this protein was measured by SDS-PAGE and reached up to 95%. It migrated to a band with a molecular weight of 90 kDa on the gel under reducing conditions. And it contains less than 1.0 EU/ug endotoxin determined by the LAL method. Its bio-activity was tested through the functional ELISA. In-stock recombinant ERBB2 protein is offered now.
ERBB2 is involved in the modulation of various vital functions, including cell growth, differentiation, and apoptosis. It is also an important player in human malignancies. Amplification or overexpression of ERBB has been reported in about 30% of human breast carcinomas and other human cancers.
Applications : Antigen, Binding assay/Protein-protein interaction
Review: ERBB2 is involved in the regulation of many important functions, including cell growth, differentiation and apoptosis. It is an important participant in human malignant tumors and one of the hot targets for current research on tumors. I used CSB-MP007763HU product for an ELISA experiment, EC50 was 1.212-3.812 ng/ml, and the protein had complete biological activity. Subsequent screening of antibodies resulted in more high-quality antibodies, indicating good protein performance! The subsequent experiment was very smooth!
By Anonymous
Applications : Antigen, Binding assay/Protein-protein interaction
Review: After receiving the product, we conducted SDS detection and functional ELISA verification, and the results showed that the protein purity was higher than the standard, and there were no impurity bands. The binding activity with antibodies was good, and the EC50 was 1.212-3.812 ng/ml. After immunizing the mouse, the serum titer was high, and the ELISA testing effect of the coated protein was good. In-stock products with fast delivery, good packaging, stable protein performance, and good repeatability! We will continue to purchase in large quantities!
By Anonymous