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FYN is a non-receptor or cytoplasmatic tyrosine kinase (TK) belonging to the Src family kinases (SFKs) involved in multiple transduction pathways in the central nervous system (CNS) including synaptic transmission, myelination, axon guidance, and oligodendrocyte formation. FYN is thought to function at synaptic sites and act as a key regulator in synaptic transmission and plasticity. When disrupted by these pathways, FYN can contribute to the development of severe brain pathologies, such as Alzheimer’s disease (AD) and multiple sclerosis (MS). FYN also participates in growth factor and cytokine receptor signaling, ion channel function, platelet activation, fertilization, entry into mitosis, and other additional biological functions.The production of this recombinant FYN antibody started with identifying and cloning the genes for antibody expression. After the FYN antibody was cloned into an expression plasmid, the plasmid could be introduced into the mammalian cell to produce the target recombinant antibody. This recombinant FYN antibody has been validated in ELISA, IHC.
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