The ADCYAP1R1 gene encodes the ADCYAP receptor type I, also known as PAC1R. This receptor is a G-protein coupled receptor that mediates the effects of pituitary adenylate cyclase-activating polypeptide (PACAP) in the central nervous system. It is involved in stress response and fear regulation, playing a critical role in the hypothalamic-pituitary-adrenal axis and the amygdala. ADCYAP1R1 is associated with post-traumatic stress disorder (PTSD) and anxiety, and its dysregulation may contribute to these conditions. Research into ADCYAP1R1 has led to potential therapeutic targets for PTSD and anxiety disorders, with ongoing drug development efforts focusing on PACAP receptor antagonists.
ADCYAP1R1 Antibody (CSB-PA207627)
Validated Data
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA207627(ADCYAP1R1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA207627(ADCYAP1R1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Hela cells, Mouse stomach tissue, Mouse brain tissue, Primary antibody: CSB-PA207627(ADCYAP1R1 Antibody) at dilution 1/2000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
The following ADCYAP1R1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ADCYAP1R1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA207627 | ADCYAP1R1 Antibody | Human,Mouse | ELISA,WB,IHC |
ADCYAP1R1 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-CF001347HU | Recombinant Human Pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1) | in vitro E.coli expression system |
CSB-YP001347HU1 CSB-EP001347HU1 CSB-BP001347HU1 CSB-MP001347HU1 CSB-EP001347HU1-B |
Recombinant Human Pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADCYAP1R1 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-CF642772BO | Recombinant Bovine Pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1) | in vitro E.coli expression system |
CSB-YP642772BO1 CSB-EP642772BO1 CSB-BP642772BO1 CSB-MP642772BO1 CSB-EP642772BO1-B |
Recombinant Bovine Pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADCYAP1R1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-CF001347MO | Recombinant Mouse Pituitary adenylate cyclase-activating polypeptide type I receptor (Adcyap1r1) | in vitro E.coli expression system |
CSB-YP001347MO1 CSB-EP001347MO1 CSB-BP001347MO1 CSB-MP001347MO1 CSB-EP001347MO1-B |
Recombinant Mouse Pituitary adenylate cyclase-activating polypeptide type I receptor (Adcyap1r1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ADCYAP1R1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-CF001347RA | Recombinant Rat Pituitary adenylate cyclase-activating polypeptide type IA receptor (Adcyap1r1) | in vitro E.coli expression system |
CSB-YP001347RA1 CSB-EP001347RA1 CSB-BP001347RA1 CSB-MP001347RA1 CSB-EP001347RA1-B |
Recombinant Rat Pituitary adenylate cyclase-activating polypeptide type IA receptor (Adcyap1r1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |