BAX

BAX (BCL2-associated X protein), alias Bcl-2-like protein 4, is a core pro-apoptotic member of the BCL-2 family. It localizes to mitochondria, oligomerizes to form pores in the outer membrane, releasing cytochrome c to trigger caspase-mediated cell death. It antagonizes anti-apoptotic BCL-2 proteins, balancing intrinsic apoptotic pathways.
Dysregulated BAX (low expression/function) contributes to cancers like lung and breast by enabling tumor survival. It’s also linked to neurodegeneration. BH3 mimetics (e.g., navitoclax) disrupt BAX-inhibiting interactions, restoring its activity; these are in clinical trials for hematological malignancies, showing promise in inducing apoptosis in resistant cells.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

BAX Antibody (CSB-PA000978)

Validated Data

Western Blot analysis of HeLa cells using Bax Polyclonal Antibody

Western Blot analysis of MCF7 KB cells using Bax Polyclonal Antibody

Human Apoptosis regulator BAX ELISA Kit (CSB-E09344h)

Validated Data

Code: CSB-E09344h

Size: 96T,5×96T,10×96T

Sensitivity: 0.312 ng/mL

Detection Range: 1.25 ng/mL-80 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following BAX reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

BAX Antibodies

BAX Proteins

BAX ELISA Kits

BAX Antibodies

BAX Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA002573GA01HU	BAX Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA834415	BAX (Ab-167) Antibody	Human,Mouse	ELISA,WB,IF
CSB-PA167247	BAX Antibody	Human,Rat	ELISA,WB,IHC,IF
CSB-PA000976	BAX Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA000977	BAX Antibody	Human,Mouse,Rat	WB, IF, ELISA
CSB-PA000978	BAX Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA040116	Phospho-BAX (S184) Antibody	Human,Mouse,Rat	IHC, ELISA
CSB-PA040117	Phospho-BAX (T167) Antibody	Human,Mouse,Rat	IF, ELISA
CSB-PA040120	BAX Antibody	Human,Mouse,Rat	IHC, ELISA
CSB-PA221042	BAX Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA052042	BAX Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-MA183751	BAX Monoclonal Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-MA484077	BAX Monoclonal Antibody	Human, Mouse, Rat	ELISA, WB, IHC
CSB-RA116135A0HU	BAX Recombinant Monoclonal Antibody	Human, Mouse	ELISA, IHC, FC
CSB-RA002573MA1HU	BAX Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC, FC

BAX Antibodies for Escherichia coli (strain K12)

Code	Product Name	Species Reactivity	Application
CSB-PA328699XA01ENV	bax Antibody	Escherichia coli (strain K12)	ELISA, WB (ensure identification of antigen)

BAX Proteins

BAX Proteins for Escherichia coli (strain K12)

Code	Product Name	Source
CSB-YP328699ENV CSB-EP328699ENV CSB-BP328699ENV CSB-MP328699ENV CSB-EP328699ENV-B	Recombinant Escherichia coli Protein bax (bax)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BAX Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-CF720536RA	Recombinant Rat Apoptosis regulator BAX (Bax)	in vitro E.coli expression system
CSB-YP720536RA1 CSB-EP720536RA1 CSB-BP720536RA1 CSB-MP720536RA1 CSB-EP720536RA1-B	Recombinant Rat Apoptosis regulator BAX (Bax), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BAX Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-CF002573BO	Recombinant Bovine Apoptosis regulator BAX (BAX)	in vitro E.coli expression system
CSB-YP002573BO1 CSB-EP002573BO1 CSB-BP002573BO1 CSB-MP002573BO1 CSB-EP002573BO1-B	Recombinant Bovine Apoptosis regulator BAX (BAX), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BAX Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF002573HU(A4)	Recombinant Human Apoptosis regulator BAX (BAX)	in vitro E.coli expression system
CSB-CF002573HU(A4)e0	Recombinant Human Apoptosis regulator BAX (BAX)	in vitro E.coli expression system
CSB-CF002573HU(A4)c0	Recombinant Human Apoptosis regulator BAX (BAX)	in vitro E.coli expression system
CSB-MP002573HU(A4)	Recombinant Human Apoptosis regulator BAX (BAX)-VLPs	Mammalian cell

BAX ELISA Kit

BAX ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E09344h	Human Apoptosis regulator BAX ELISA Kit	serum, plasma, tissue homogenates	0.312 ng/mL

BAX ELISA Kit for Rattus norvegicus (Rat)

Code	Product Name	Sample Types	Sensitivity
CSB-EL002573RA	Rat Apoptosis regulator BAX(BAX) ELISA kit	serum, plasma, tissue homogenates, cell lysates	15.6 pg/mL

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BAX

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