CASP8

CASP8, full name caspase-8. It is a key mediator of programmed cell death, eliminating damaged abnormal cells and maintaining normal cell renewal and immune homeostasis in human body.
Inactivated CASP8 induces tumors and autoimmune diseases, while overactivation causes inflammatory and neural damage. CASP8 modulators are under preclinical and early clinical development for cancer and inflammatory disorders.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CASP8 Antibody (CSB-PA18109A0Rb)

Validated Data

Western blot
All lanes: CASP8 antibody at 2µg/ml
Lane 1: ACCM whole cell lysate
Lane 2: LO2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 56, 54, 46, 58, 28, 26, 33, 31, 62 kDa
Observed band size: 56 kDa

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA18109A0Rb at dilution of 1:20

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA18109A0Rb at dilution of 1:20

Immunofluorescent analysis of HepG2 cells using CSB-PA18109A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human Caspase 8(Casp-8) ELISA Kit (CSB-E13636h)

Validated Data

Code: CSB-E13636h

Size: 96T,5×96T,10×96T

Sensitivity: 7.81 pg/ml

Detection Range: 31.25 pg/mL-2000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following CASP8 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CASP8 Antibodies

CASP8 Proteins

CASP8 ELISA Kits

CASP8 Antibodies

CASP8 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA18109B0Rb	CASP8 Antibody, HRP conjugated	Human	ELISA
CSB-PA004553GA01HU	CASP8 Antibody	Human	ELISA,WB,IHC
CSB-PA18109A0Rb	CASP8 Antibody	Human	ELISA, WB, IHC, IF
CSB-PA982156	CASP8 Antibody	Human	ELISA,WB
CSB-PA000009	Cleaved-CASP8 (D384) Antibody	Human	WB, ELISA
CSB-PA000653	Phospho-CASP8 (Y380) Antibody	Human	WB, ELISA
CSB-PA001234	CASP8 Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA060299	Phospho-CASP8 (S347) Antibody	Human,Rat	WB, IHC, ELISA
CSB-MA080171	CASP8 Monoclonal Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA080234	CASP8 Antibody	Human,Mouse,Rat	WB, IHC
CSB-PA181094ZA01HU	CASP8 Antibody	Homo sapiens	ELISA, WB (ensure identification of antigen)
CSB-RA549188A0HU	CASP8 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC, IF, FC

CASP8 Proteins

CASP8 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP004553MO CSB-EP004553MO CSB-BP004553MO CSB-MP004553MO CSB-EP004553MO-B	Recombinant Mouse Caspase-8 (Casp8)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CASP8 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-BP621791HU CSB-MP621791HU CSB-EP621791HU-B	Recombinant Human Caspase-8 (CASP8), partial	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP621791HU	Recombinant Human Caspase-8 (CASP8), partial	E.coli
CSB-EP621791HUc7	Recombinant Human Caspase-8 (CASP8), partial	E.coli
CSB-YP621791HU	Recombinant Human Caspase-8 (CASP8), partial	Yeast

CASP8 ELISA Kit

CASP8 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E13636h	Human Caspase 8(Casp-8) ELISA Kit	serum, plasma, cell lysates	7.81 pg/ml

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CASP8

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