Clusterin is a protein in humans that is encoded by CLU gene. Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation. Secreted isoform 1 protects cells against apoptosis and against cytolysis by complement.

CLU Antibodies

CLU Antibodies for Homo sapiens (Human)

CLU Antibodies for Human

CLU Proteins

CLU Proteins for Homo sapiens (Human)

CLU Proteins for Ovis aries (Sheep)

CLU Proteins for Bos taurus (Bovine)

CLU Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

CLU Proteins for Mesocricetus auratus (Golden hamster)

CLU Proteins for Coturnix japonica (Japanese quail) (Coturnix coturnix japonica)

CLU Proteins for Rattus norvegicus (Rat)

CLU Proteins for Oryctolagus cuniculus (Rabbit)

CLU Proteins for Sus scrofa (Pig)

CLU Proteins for Equus caballus (Horse)


CLU ELISA Kit for Bos taurus (Bovine)

CLU ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

CLU ELISA Kit for Equus caballus (Horse)

CLU ELISA Kit for Homo sapiens (Human)

CLU ELISA Kit for Mus musculus (Mouse)

CLU ELISA Kit for Sus scrofa (Pig)

CLU ELISA Kit for Oryctolagus cuniculus (Rabbit)

CLU ELISA Kit for Rattus norvegicus (Rat)

CLU ELISA Kit for Ovis aries (Sheep)


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