CLU

Clusterin is a protein in humans that is encoded by CLU gene. Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation. Secreted isoform 1 protects cells against apoptosis and against cytolysis by complement.

CLU Antibodies

CLU Antibodies for Homo sapiens (Human)

CLU Antibodies for Drosophila ananassae (Fruit fly)

CLU Antibodies for Drosophila erecta (Fruit fly)

CLU Antibodies for Drosophila melanogaster (Fruit fly)

CLU Antibodies for Drosophila yakuba (Fruit fly)

CLU Proteins

CLU Proteins for Homo sapiens (Human)

CLU Proteins for Ovis aries (Sheep)

CLU Proteins for Bos taurus (Bovine)

CLU Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

CLU Proteins for Mesocricetus auratus (Golden hamster)

CLU Proteins for Coturnix japonica (Japanese quail) (Coturnix coturnix japonica)

CLU Proteins for Rattus norvegicus (Rat)

CLU Proteins for Drosophila melanogaster (Fruit fly)

CLU Proteins for Drosophila ananassae (Fruit fly)

CLU Proteins for Drosophila virilis (Fruit fly)

CLU Proteins for Drosophila yakuba (Fruit fly)

CLU Proteins for Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)

CLU Proteins for Drosophila willistoni (Fruit fly)

CLU Proteins for Drosophila erecta (Fruit fly)

CLU Proteins for Drosophila mojavensis (Fruit fly)

CLU Proteins for Drosophila persimilis (Fruit fly)

CLU Proteins for Oryctolagus cuniculus (Rabbit)

CLU Proteins for Sus scrofa (Pig)

CLU Proteins for Equus caballus (Horse)

CLU Proteins for Drosophila pseudoobscura pseudoobscura (Fruit fly)

CLU ELISA Kit

CLU ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

CLU ELISA Kit for Equus caballus (Horse)

CLU ELISA Kit for Homo sapiens (Human)

CLU ELISA Kit for Mus musculus (Mouse)

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