CLU

Clusterin is a protein in humans that is encoded by CLU gene. Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. Does not refold proteins by itself. Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation. Secreted isoform 1 protects cells against apoptosis and against cytolysis by complement.

The following CLU reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CLU Antibodies

CLU Proteins

CLU ELISA Kits

CLU Antibodies

CLU Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA005595GA01HU	CLU Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA06029A0Rb	CLU Antibody	Human	ELISA, IHC, IF
CSB-PA06029D0Rb	CLU Antibody, Biotin conjugated	Human	ELISA
CSB-PA001725	CLU Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA117475	CLU Antibody	Human	ELISA,IHC
CSB-RA449834A0HU	CLU Recombinant Monoclonal Antibody	Human	ELISA, IHC

CLU Antibodies for Drosophila ananassae (Fruit fly)

Code	Product Name	Species Reactivity	Application
CSB-PA453413XA01DKY	clu Antibody	Drosophila ananassae (Fruit fly)	ELISA, WB (ensure identification of antigen)

CLU Antibodies for Drosophila erecta (Fruit fly)

Code	Product Name	Species Reactivity	Application
CSB-PA459260XA01DLK	clu Antibody	Drosophila erecta (Fruit fly)	ELISA, WB (ensure identification of antigen)

CLU Antibodies for Drosophila melanogaster (Fruit fly)

Code	Product Name	Species Reactivity	Application
CSB-PA381782XA01DLU	clu Antibody	Drosophila melanogaster (Fruit fly)	ELISA, WB (ensure identification of antigen)

CLU Antibodies for Drosophila yakuba (Fruit fly)

Code	Product Name	Species Reactivity	Application
CSB-PA453840XA01DMR	clu Antibody	Drosophila yakuba (Fruit fly)	ELISA, WB (ensure identification of antigen)

CLU Proteins

CLU Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP005595HU CSB-BP005595HU CSB-EP005595HU-B	Recombinant Human Clusterin (CLU)	Yeast Baculovirus In Vivo Biotinylation in E.coli
CSB-EP005595HU	Recombinant Human Clusterin (CLU)	E.coli
CSB-EP005595HU1	Recombinant Human Clusterin (CLU), partial	E.coli

CLU Proteins for Ovis aries (Sheep)

Code	Product Name	Source
CSB-YP005595SH CSB-EP005595SH CSB-BP005595SH CSB-MP005595SH CSB-EP005595SH-B	Recombinant Sheep Clusterin (CLU)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP005595BO CSB-EP005595BO CSB-BP005595BO CSB-MP005595BO CSB-EP005595BO-B	Recombinant Bovine Clusterin (CLU)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP005595DO CSB-EP005595DO CSB-BP005595DO CSB-MP005595DO CSB-EP005595DO-B	Recombinant Dog Clusterin (CLU)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Mesocricetus auratus (Golden hamster)

Code	Product Name	Source
CSB-YP005595MRG CSB-BP005595MRG CSB-MP005595MRG CSB-EP005595MRG-B	Recombinant Mesocricetus auratus Clusterin (CLU)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Coturnix japonica (Japanese quail) (Coturnix coturnix japonica)

Code	Product Name	Source
CSB-YP005595DXJ CSB-EP005595DXJ CSB-BP005595DXJ CSB-MP005595DXJ CSB-EP005595DXJ-B	Recombinant Coturnix coturnix japonica Clusterin (CLU)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP005595RA CSB-EP005595RA CSB-BP005595RA CSB-MP005595RA CSB-EP005595RA-B	Recombinant Rat Clusterin (Clu)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Drosophila melanogaster (Fruit fly)

Code	Product Name	Source
CSB-YP381782DLU CSB-EP381782DLU CSB-BP381782DLU CSB-MP381782DLU CSB-EP381782DLU-B	Recombinant Drosophila melanogaster Protein KIAA0664 homolog (CG8443), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Drosophila ananassae (Fruit fly)

Code	Product Name	Source
CSB-YP453413DKY CSB-EP453413DKY CSB-BP453413DKY CSB-MP453413DKY CSB-EP453413DKY-B	Recombinant Drosophila ananassae Protein KIAA0664 homolog (GF12179), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Drosophila virilis (Fruit fly)

Code	Product Name	Source
CSB-YP453814DMP CSB-EP453814DMP CSB-BP453814DMP CSB-MP453814DMP CSB-EP453814DMP-B	Recombinant Drosophila virilis Protein KIAA0664 homolog (GJ21424), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Drosophila yakuba (Fruit fly)

Code	Product Name	Source
CSB-YP453840DMR CSB-EP453840DMR CSB-BP453840DMR CSB-MP453840DMR CSB-EP453840DMR-B	Recombinant Drosophila yakuba Protein KIAA0664 homolog (GE11763), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi)

Code	Product Name	Source
CSB-YP455749DLL CSB-EP455749DLL CSB-BP455749DLL CSB-MP455749DLL CSB-EP455749DLL-B	Recombinant Drosophila grimshawi Protein KIAA0664 homolog (GH22778), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Drosophila willistoni (Fruit fly)

Code	Product Name	Source
CSB-YP457700DMQ CSB-EP457700DMQ CSB-BP457700DMQ CSB-MP457700DMQ CSB-EP457700DMQ-B	Recombinant Drosophila willistoni Protein KIAA0664 homolog (GK22132), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Drosophila erecta (Fruit fly)

Code	Product Name	Source
CSB-YP459260DLK CSB-EP459260DLK CSB-BP459260DLK CSB-MP459260DLK CSB-EP459260DLK-B	Recombinant Drosophila erecta Protein KIAA0664 homolog (GG20578), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Drosophila mojavensis (Fruit fly)

Code	Product Name	Source
CSB-YP459632DLY CSB-EP459632DLY CSB-BP459632DLY CSB-MP459632DLY CSB-EP459632DLY-B	Recombinant Drosophila mojavensis Protein KIAA0664 homolog (GI20574), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Drosophila persimilis (Fruit fly)

Code	Product Name	Source
CSB-YP461540DMB CSB-EP461540DMB CSB-BP461540DMB CSB-MP461540DMB CSB-EP461540DMB-B	Recombinant Drosophila persimilis Protein KIAA0664 homolog (GL11405), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP005595RB CSB-EP005595RB CSB-BP005595RB CSB-MP005595RB CSB-EP005595RB-B	Recombinant Rabbit Clusterin (CLU)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP005595PI CSB-EP005595PI CSB-BP005595PI CSB-MP005595PI CSB-EP005595PI-B	Recombinant Pig Clusterin (CLU)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Equus caballus (Horse)

Code	Product Name	Source
CSB-YP005595HO CSB-EP005595HO CSB-BP005595HO CSB-MP005595HO CSB-EP005595HO-B	Recombinant Horse Clusterin (CLU)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU Proteins for Drosophila pseudoobscura pseudoobscura (Fruit fly)

Code	Product Name	Source
CSB-YP640896DME CSB-EP640896DME CSB-BP640896DME CSB-MP640896DME CSB-EP640896DME-B	Recombinant Drosophila pseudoobscura pseudoobscura Protein KIAA0664 homolog (GA21082), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CLU ELISA Kit

CLU ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Sample Types	Sensitivity
CSB-E13770c	Dog clusterin,CLU ELISA Kit	serum, plasma, tissue homogenates	4.963 ng/mL

CLU ELISA Kit for Equus caballus (Horse)

Code	Product Name	Sample Types	Sensitivity
CSB-EL005595HO	Horse Clusterin(CLU) ELISA kit	serum, plasma, tissue homogenates	3.9 ng/mL

CLU ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E09121h	Human clusterin,CLU ELISA Kit	serum, plasma, cell culture supernates, saliva, urine	0.78 ng/mL

CLU ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-EL005595MO	Mouse Clusterin(CLU) ELISA kit	serum, plasma, cell culture supernates, tissue homogenates	0.277 ng/mL

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