Code | CSB-RA449834A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
CLU, an extracellular chaperone and cell function regulator, is diminished in pulmonary fibrosis patients' bronchoalveolar lavage fluid. It regulates cell proliferation, differentiation, and survival in epithelial cells, smooth muscle cells, and synoviocytes. Replicated genome-wide studies have shown that genetic variation in the CLU gene has been linked to Alzheimer's disease (AD), and plasma clusterin levels have been linked to brain atrophy, baseline prevalence and severity, and rapid clinical progression in patients with AD, highlighting the importance of clusterin in AD pathogenesis.
CUSABIO designed the vector clones for the expression of a recombinant CLU antibody in mammalian cells. The vector clones were obtained by inserting the CLU antibody heavy and light chains into the plasma vectors. The recombinant CLU antibody was purified from the culture medium through Affinity-chromatography. It can be used to detect CLU protein from Human in the ELISA, IHC.There are currently no reviews for this product.