Crk-like proteinis a protein in humans that is encoded by CRKL gene. Crk-like protein is a protein that in humans is encoded by the CRKL gene. v-CRK avian sarcoma virus CT10-homolog-like contains one SH2 domain and two SH3 domains. CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential. CrkL together with Crk participates in the Reelin signaling cascade downstream of DAB1.
The following CRKL reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
CRKL Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA000736 | Phospho-CRKL (Y207) Antibody |
Human,Mouse,Rat,Monkey | WB, IHC, IF, ELISA |
CSB-PA001790 | CRKL Antibody |
Human,Mouse,Rat,Monkey | WB, IHC, IF, ELISA |
CSB-PA831164 | CRKL Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA129519 | CRKL Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA005980LA01HU | CRKL Antibody |
Human | ELISA, WB, IF |
CSB-PA005980LC01HU | CRKL Antibody, FITC conjugated |
Human |
CRKL Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP005980HU CSB-EP005980HU CSB-BP005980HU CSB-MP005980HU CSB-EP005980HU-B |
Recombinant Human Crk-like protein (CRKL) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CRKL Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP005980MO CSB-EP005980MO CSB-BP005980MO CSB-MP005980MO CSB-EP005980MO-B |
Recombinant Mouse Crk-like protein (Crkl) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CRKL Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP719444RA CSB-EP719444RA CSB-BP719444RA CSB-MP719444RA CSB-EP719444RA-B |
Recombinant Rat Crk-like protein (Crkl) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |