Crk-like proteinis a protein in humans that is encoded by CRKL gene. Crk-like protein is a protein that in humans is encoded by the CRKL gene. v-CRK avian sarcoma virus CT10-homolog-like contains one SH2 domain and two SH3 domains. CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential. CrkL together with Crk participates in the Reelin signaling cascade downstream of DAB1.

CRKL Antibodies

CRKL Antibodies for Homo sapiens (Human)

CRKL Proteins

CRKL Proteins for Homo sapiens (Human)

CRKL Proteins for Mus musculus (Mouse)

CRKL Proteins for Rattus norvegicus (Rat)


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