GSK3B

Glycogen synthase kinase-3 beta is a protein in humans that is encoded by GSK3B gene. Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Requires primed phosphorylation of the majority of its substrates. In skeletal muscle, contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. May also mediate the development of insulin resistance by regulating activation of transcription factors. Regulates protein synthesis by controlling the activity of initiation factor 2B (EIF2BE/EIF2B5) in the same manner as glycogen synthase.

GSK3B Antibodies

GSK3B Antibodies for Homo sapiens (Human)

Code Product Name Species Reactivity Application
CSB-PA009963GA01HU GSK3B Antibody Human,Mouse,Rat,Pig ELISA,WB
CSB-PA120951 GSK3B (Ab-9) Antibody Human,Mouse,Rat ELISA,WB,IHC,IF
CSB-PA166926 Phospho-GSK3B (Ser9) Antibody Human,Mouse,Rat ELISA,WB,IHC,IF
CSB-PA939628 GSK3B Antibody Human,Mouse,Rat ELISA,WB
CSB-PA000536 Phospho-GSK3B (S9) Antibody Human,Mouse,Rat WB,IHC,IP,ELISA
CSB-PA000636 Phospho-GSK3B (S9) Antibody Human,Mouse,Rat WB,IHC,ELISA
CSB-PA002848 GSK3B Antibody Human,Mouse,Rat WB,IHC,IP,ELISA
CSB-PA009038 GSK3B Antibody Human,Mouse,Rat WB,IHC,ELISA
CSB-PA080166 GSK3B Antibody Mouse,Rat WB,IHC
CSB-RA009963A09phHU Phospho-GSK3B (Ser9) Antibody Human ELISA, WB, IHC, IF

GSK3B Antibodies for Human

Code Product Name Species Reactivity Application
CSB-PA009963LA01HU GSK3B Antibody Human, Mouse ELISA, WB, IF
CSB-PA009963LB01HU GSK3B Antibody, HRP conjugated Human ELISA
CSB-PA009963LC01HU GSK3B Antibody, FITC conjugated Human ELISA
CSB-PA009963LD01HU GSK3B Antibody, Biotin conjugated Human ELISA

GSK3B Proteins

GSK3B Proteins for Rattus norvegicus (Rat)

Code Product Name Source
CSB-YP009963RA Recombinant Rat Glycogen synthase kinase-3 beta(Gsk3b),Yeast Yeast
CSB-EP009963RA Recombinant Rat Glycogen synthase kinase-3 beta(Gsk3b),Escherichia Coli E.coli
CSB-BP009963RA Recombinant Rat Glycogen synthase kinase-3 beta(Gsk3b),Baculovirus Baculovirus
CSB-MP009963RA Recombinant Rat Glycogen synthase kinase-3 beta(Gsk3b),Mammalian cell Mammalian cell

GSK3B Proteins for Homo sapiens (Human)

Code Product Name Source
CSB-YP009963HU Recombinant Human Glycogen synthase kinase-3 beta(GSK3B) Yeast
CSB-EP009963HU Recombinant Human Glycogen synthase kinase-3 beta(GSK3B) E.coli
CSB-BP009963HU Recombinant Human Glycogen synthase kinase-3 beta(GSK3B),Baculovirus Baculovirus
CSB-MP009963HU Recombinant Human Glycogen synthase kinase-3 beta(GSK3B),Mammalian cell Mammalian cell

GSK3B Proteins for Spermophilus citellus (European suslik) (Citellus citellus)

Code Product Name Source
CSB-YP723085SJE Recombinant Spermophilus citellus Glycogen synthase kinase-3 beta(GSK3B),Yeast Yeast
CSB-EP723085SJE Recombinant Spermophilus citellus Glycogen synthase kinase-3 beta(GSK3B),Escherichia Coli E.coli
CSB-BP723085SJE Recombinant Spermophilus citellus Glycogen synthase kinase-3 beta(GSK3B),Baculovirus Baculovirus
CSB-MP723085SJE Recombinant Spermophilus citellus Glycogen synthase kinase-3 beta(GSK3B),Mammalian cell Mammalian cell

GSK3B Proteins for Xenopus laevis (African clawed frog)

Code Product Name Source
CSB-YP856250XBE Recombinant Xenopus laevis Glycogen synthase kinase-3 beta(gsk3b),Yeast Yeast
CSB-EP856250XBE Recombinant Xenopus laevis Glycogen synthase kinase-3 beta(gsk3b),Escherichia Coli E.coli
CSB-BP856250XBE Recombinant Xenopus laevis Glycogen synthase kinase-3 beta(gsk3b),Baculovirus Baculovirus
CSB-MP856250XBE Recombinant Xenopus laevis Glycogen synthase kinase-3 beta(gsk3b),Mammalian cell Mammalian cell

GSK3B Proteins for Mus musculus (Mouse)

Code Product Name Source
CSB-YP892998MO Recombinant Mouse Glycogen synthase kinase-3 beta(Gsk3b),Yeast Yeast
CSB-EP892998MO Recombinant Mouse Glycogen synthase kinase-3 beta(Gsk3b),Escherichia Coli E.coli
CSB-BP892998MO Recombinant Mouse Glycogen synthase kinase-3 beta(Gsk3b),Baculovirus Baculovirus
CSB-MP892998MO Recombinant Mouse Glycogen synthase kinase-3 beta(Gsk3b),Mammalian cell Mammalian cell

GSK3B cDNA

GSK3B cDNA for Xenopus laevis (African clawed frog)

Code Product Name Vector Accession NO.
CSB-CL856250XBE gsk3b pUC NM_001090283.1

GSK3B cDNA for Rattus norvegicus (Rat)

Code Product Name Vector Accession NO.
CSB-CL009963RA Gsk3b pUC NM_032080.1

GSK3B ELISA Kit

GSK3B ELISA Kit for Homo sapiens (Human)

Code Product Name Sample Types Sensitivity
CSB-EL009963HU Human Glycogen synthase kinase-3 beta(GSK3B) ELISA kit serum, plasma, tissue homogenates 3.12 pg/mL

GSK3B ELISA Kit for Rattus norvegicus (Rat)

Code Product Name Sample Types Sensitivity
CSB-EL009963RA Rat Glycogen synthase kinase-3 beta(GSK3B) ELISA kit serum, plasma, tissue homogenates, cell lysates 0.039 ng/mL

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