IFNLR1

Interferon lambda receptor 1 is a protein in humans that is encoded by IFNLR1 gene. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts.

IFNLR1 Antibodies

IFNLR1 Antibodies for Homo sapiens (Human)

IFNLR1 Proteins

IFNLR1 Proteins for Mus musculus (Mouse)

IFNLR1 Proteins for Homo sapiens (Human)

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