KIT

Mast/stem cell growth factor receptor Kit is a protein in humans that is encoded by KIT gene. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activated KIT also transmits signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3, STAT5A and STAT5B.

KIT Antibodies

KIT Antibodies for Homo sapiens (Human)

KIT Proteins

KIT Proteins for Homo sapiens (Human)

KIT Proteins for Bos taurus (Bovine)

KIT Proteins for Mus musculus (Mouse)

KIT Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

KIT Proteins for Gallus gallus (Chicken)

KIT Proteins for Felis catus (Cat) (Felis silvestris catus)

KIT Proteins for Capra hircus (Goat)

KIT Proteins for Sus scrofa (Pig)

KIT Proteins for Callithrix jacchus (White-tufted-ear marmoset)

KIT Proteins for Takifugu rubripes (Japanese pufferfish) (Fugu rubripes)

KIT Proteins for Xenopus laevis (African clawed frog)

KIT ELISA Kit

KIT ELISA Kit for Mus musculus (Mouse)

KIT ELISA Kit for Homo sapiens (Human)

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