KLF4, or GKLF and EZF, is a transcription factor predominantly expressed in colon and gastric cancer tissues. It is involved in cell proliferation, differentiation, and embryonic development. KLF4 directly regulates gene transcription by binding to promoter elements, exhibiting both tumor-suppressive and -promoting effects. It plays a significant role in tumorigenesis and vascular remodeling and is a key inducer for reprogramming somatic cells into iPS cells, offering potential for gene therapy applications in clinical medicine.
KLF4 Antibody (CSB-PA012394DSR2HU)
Validated Data
Western blot
All lanes: Krueppel-like factor 4 antibody at 5μg/ml + 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 55, 52, 46, 13, 7 kDa
Observed band size: 55 kDa
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA012394DSR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA012394DSR2HU at dilution of 1:100
Human Krueppel-like factor 4(KLF4) ELISA kit (CSB-EL012394HU)
Validated Data
Code: CSB-EL012394HU
Size: 96T,5×96T,10×96T
Sensitivity: 4.6 pg/mL
Detection Range: 18.75 pg/mL-1200 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following KLF4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
KLF4 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA012394GA01HU | KLF4 Antibody | Human,Mouse,Rat | ELISA,WB,IF |
CSB-PA012394DSR2HU | KLF4 Antibody | Human | ELISA, WB, IHC |
CSB-RA194949A0HU | KLF4 Recombinant Monoclonal Antibody | Human | ELISA, WB, IHC, IF, IP |
KLF4 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP012394HU CSB-EP012394HU CSB-BP012394HU CSB-MP012394HU CSB-EP012394HU-B |
Recombinant Human Krueppel-like factor 4 (KLF4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KLF4 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP730657MO CSB-EP730657MO CSB-BP730657MO CSB-MP730657MO CSB-EP730657MO-B |
Recombinant Mouse Krueppel-like factor 4 (Klf4) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
KLF4 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL012394HU | Human Krueppel-like factor 4(KLF4) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 4.6 pg/mL |