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Protein numb homolog is a protein in humans that is encoded by NUMB gene. Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.
The following NUMB reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NUMB Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA016186GA01HU | NUMB Antibody |
Human,Mouse | ELISA,WB,IHC |
| CSB-PA005466 | NUMB Antibody |
Human,Mouse,Rat | WB, ELISA |
| CSB-PA909836 | NUMB Antibody |
Human,Mouse,Rat | ELISA,WB |
| CSB-PA016186DSR2HU | NUMB Antibody |
Human, Mouse | ELISA, WB |
NUMB Antibodies for Drosophila melanogaster (Fruit fly)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA322861XA01DLU | numb Antibody |
Drosophila melanogaster (Fruit fly) | ELISA, WB (ensure identification of antigen) |
NUMB Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP016186HU CSB-EP016186HU CSB-BP016186HU CSB-MP016186HU CSB-EP016186HU-B |
Recombinant Human Protein numb homolog (NUMB) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NUMB Proteins for Drosophila melanogaster (Fruit fly)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP322861DLU CSB-EP322861DLU CSB-BP322861DLU CSB-MP322861DLU CSB-EP322861DLU-B |
Recombinant Drosophila melanogaster Protein numb (numb), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NUMB Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP643528RA CSB-EP643528RA CSB-BP643528RA CSB-MP643528RA CSB-EP643528RA-B |
Recombinant Rat Protein numb homolog (Numb) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NUMB Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP882586MO CSB-EP882586MO CSB-BP882586MO CSB-MP882586MO CSB-EP882586MO-B |
Recombinant Mouse Protein numb homolog (Numb) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
