RELN

RELN encodes Reelin, also known as Rl, ECM13, and ARH1. Reelin is a large extracellular matrix glycoprotein. It plays a crucial role in neuronal migration and positioning during brain development by binding to the ApoER2 and VLDLR receptors, which activates the Dab1 signaling cascade. This pathway is essential for normal brain lamination.
Dysregulation of Reelin is associated with various neurological disorders, including autism, schizophrenia, and Alzheimer's disease. Given its key role, Reelin has become an attractive target in drug development. Currently, researchers are exploring agents that can modulate Reelin signaling to restore normal brain function in related diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

RELN Antibody (CSB-PA019557LA01HU)

Validated Data

Immunohistochemistry of paraffin-embedded mouse liver tissue using CSB-PA019557LA01HU at dilution of 1:100

IHC image of CSB-PA019557LA01HU diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human Reelin(RELN) ELISA kit (CSB-EL019557HU)

Validated Data

Code: CSB-EL019557HU

Size: 96T,5×96T,10×96T

Sensitivity: 0.009 ng/ml

Detection Range: 0.009 ng/ml - 7 ng/ml

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following RELN reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

RELN Antibodies

RELN Proteins

RELN ELISA Kits

RELN Antibodies

RELN Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA019557LC01HU	RELN Antibody, FITC conjugated	Human
CSB-PA019557LA01HU	RELN Antibody	Human	ELISA, IHC
CSB-PA019557LD01HU	RELN Antibody, Biotin conjugated	Human	ELISA
CSB-PA019557LB01HU	RELN Antibody, HRP conjugated	Human	ELISA

RELN Proteins

RELN Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-EP019557HU	Recombinant Human Reelin (RELN), partial	E.coli
CSB-YP019557HU	Recombinant Human Reelin (RELN), partial	Yeast
CSB-BP019557HU CSB-MP019557HU CSB-EP019557HU-B	Recombinant Human Reelin (RELN), partial	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

RELN Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP019557RA CSB-EP019557RA CSB-BP019557RA CSB-MP019557RA CSB-EP019557RA-B	Recombinant Rat Reelin (Reln), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

RELN Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP019557CH CSB-EP019557CH CSB-BP019557CH CSB-MP019557CH CSB-EP019557CH-B	Recombinant Chicken Reelin (RELN), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

RELN Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP019557MO CSB-EP019557MO CSB-BP019557MO CSB-MP019557MO CSB-EP019557MO-B	Recombinant Mouse Reelin (Reln), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

RELN Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP019557BO CSB-EP019557BO CSB-BP019557BO CSB-MP019557BO CSB-EP019557BO-B	Recombinant Bovine Reelin (RELN)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

RELN ELISA Kit

RELN ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL019557HU	Human Reelin(RELN) ELISA kit	serum, plasma, tissue homogenates	0.009 ng/ml

RELN ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-EL019557MO	Mouse Reelin(RELN) ELISA kit	serum, plasma, tissue homogenates	1.56 pg/mL

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RELN

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