TNFRSF10D Research Reagents

Tumor necrosis factor receptor superfamily member 10D is a protein in humans that is encoded by TNFRSF10D gene. Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway.

The following TNFRSF10D reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TNFRSF10D Antibodies

TNFRSF10D Antibodies for Homo sapiens (Human)

TNFRSF10D Proteins

TNFRSF10D Proteins for Homo sapiens (Human)

TNFRSF10D ELISA Kit

TNFRSF10D ELISA Kit for Homo sapiens (Human)

TNFRSF10D Background

Tumor necrosis factor receptor superfamily member 10D is a protein in humans that is encoded by the TNFRSF10D gene. It is also known as decoy receptor 2 (DCR2), or TRAIL receptor 4 (TRAILR4). TNFRSF10D contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplasmic death domain. This receptor does not induce apoptosis and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis. TNFRSF10D is a receptor for the cytotoxic ligand TRAIL. Containing a truncated death domain and hence TNFRSF10D is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis.

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