Recombinant Rhesus Macaque Interleukin-5 protein(IL5) (Active)

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Code CSB-AP003091MOW
Product Type Interleukin
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Uniprot No. P48093
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Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias IL-5, T-cell replacing factor, TRF
Species Macaca mulatta (Rhesus macaque)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 4 ng/ml, corresponding to a specific activity of >2.5x105 IU/mg.
Purity >98% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence IPTEIPASAL VKETLALLST HRTLLIANET LRIPVPVHKN HQLCTEEIFQ GIGTLESQTV QGGTVERLFK NLSLIKKYIG GQKKKCGEER RRVNQFLDYL QEFLGVMNTE WIIES
Research Area Immunology
Source E.Coli
Gene Names IL5
Expression Region 20-134aa
Tag Info Tag-Free
Mol. Weight 26.1 kDa
Protein Description Full Length of Mature Protein
PubMed ID 7561102
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Function Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
Subcellular Location Secreted
Protein Families IL-5 family
Database Links

KEGG: mcc:710622

STRING: 9544.ENSMMUP00000004183

UniGene: Mmu.3362

Pathway Jak-STAT signaling pathway
Fc epsilon RI signaling pathway
Hematopoietic cell lineage
IL-17 signaling pathway
T cell receptor signaling pathway
Th1 and Th2 cell differentiation

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