Code | CSB-EP004548HU |
MSDS | |
Size | $224 |
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To prepare this Recombinant Human CASP3 protein, the recombinant DNA was required, which was generated by fusing the CASP3 gene with N-terminal 6xHis tag sequence. Once the recombinant DNA was amplified and purified, a protein expression system, E.coli, was needed for this CASP3 protein production. After purification, a premium CASP3 recombinant proteinwas obtained. According to SDS-PAGE, its purity turns out to be 85%+.
CASP3 is a gene encoding a protein named caspase-3 (short name is CASP3) or cysteine protease CPP32 (short name is CPP32). CASP3 protein, a member of asparate-specific cysteinyl proteases family, is a small protein consists of two subunits of 12 kDa and 17 kDa. Recently, it has attracted much attention with its incredible roles in tissue differentiation, regeneration, and neural development. This enzyme is a key zymogen in cell apoptosis and is not activated until it is cleaved by initiator caspases during apoptotic flux. Except apoptosis, tt has been found involved in other biological processes, such as anterior neural tube closure, T cell homeostasis and neuron differentiation.There are currently no reviews for this product.