Code | CSB-RA003656A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:2000 |
IHC | 1:50-1:200 |
The CASP3 recombinant monoclonal antibody is synthetically generated in vitro, starting with the extraction of CASP3 antibody genes from B cells isolated from immunoreactive rabbits. These genes are then amplified and cloned into suitable phage vectors, which are subsequently introduced into mammalian cell lines to enable the production of functional antibodies in substantial quantities. Following this, the CASP3 recombinant monoclonal antibody is purified from the culture supernatant of the transfected cell lines through affinity chromatography. This antibody can react with human CASP3 protein and has been tested for ELISA, WB, and IHC applications.
CASP3 is a critical enzyme in apoptosis, serving as an executioner that dismantles and disposes of cells in a controlled and regulated manner. Its role is essential for tissue development, maintenance of tissue homeostasis, and preventing the survival of damaged or harmful cells.
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