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The FGFR2 recombinant monoclonal antibody is a highly specific antibody against the FGFR2 protein. This FGFR2 antibody was expressed through the clone of the DNA sequence encoding the FGFR2 monoclonal antibody into plasmids and subsequent transfection into cell lines. The FGFR2 monoclonal antibody was produced from the animals immunized using the synthesized peptide derived from the human FGFR2. The isotype of this FGFR2 antibody matches with the rabbit IgG. This FGFR2 antibody can be used in ELISA and WB applications and recognizes the FGFR2 protein from human, mouse, and rat samples. It has been purified through affinity chromatography.
FGFR2 amplifications have been detected in about 10% of gastric cancer (GC) and in only 1 to 2% of breast cancer. Seung Tae Kim et al. found that PRO-007, a newly developed recombinant monoclonal antibody against FGFR2, is a potential therapeutic agent for treating gastric cancer patients with FGFR2 amplification.
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