Code | CSB-RA011972A63phHU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
IHC | 1:50-1:200 |
IF | 1:20-1:200 |
CUSABIO designed the vector clones for the expression of a recombinant JUN antibody in mammalian cells. The vector clones were obtained by inserting the JUN antibody heavy and light chains into the plasma vectors. The recombinant JUN antibody was purified from the culture medium through affinity-chromatography. It can be used to detect JUN protein from Human in the ELISA, WB, IHC, IF.
The phospho-JUN (S63) antibody can be used to detect the endogenous levels of the JUN phosphorylated at Ser63 residue. The phosphorylation of Ser63 in the NH2-terminal transactivation domain of JUN is required for its transcriptional activity. The phosphorylation of JUN has also been linked to the mediation of apoptosis when survival signals are interrupted. JUN is involved in various cellular processes, including proliferation, apoptosis, survival, tumorigenesis, and tissue morphogenesis.
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