Purity
Greater than 95% as determined by SDS-PAGE.
Endotoxin
Less than 1.0 EU/μg as determined by LAL method.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human FMC63 at 2μg/ml can bind Human CD19-Fc, the ED50 of Recombinant Human CD19-Fc is 55.28 ng/ml.
Alternative Names
CD19; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Differentiation antigen CD19; T-cell surface antigen Leu-12; CD antigen CD19
Species
Homo sapiens (Human)
Expression Region
20-291aa
Complete Sequence
PEEPLVVKVEEGDNAVLQCLKGTSDGPTQQLTWSRESPLKPFLKLSLGLPGLGIHMRPLAIWLFIFNVSQQMGGFYLCQPGPPSEKAWQPGWTVNVEGSGELFRWNVSDLGGLGCGLKNRSSEGPSSPSGKLMSPKLYVWAKDRPEIWEGEPPCLPPRDSLNQSLSQDLTMAPGSTLWLSCGVPPDSVSRGPLSWTHVHPKGPKSLLSLELKDDRPARDMWVMETGLLLPRATAQDAGKYYCHRGNLTMSFHLEITARPVLWHWLLRTGGWK
Protein Length
Extracellular Domain
Tag Info
C-terminal hFc-tagged
Form
Liquid or Lyophilized powder
Buffer
Lyophilized from a 0.2 μm filtered 20mM PB, 150mM NaCl, pH 7.4
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw
cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized
form is 12 months at -20°C/-80°C.
Lead Time
Basically, we can dispatch the products out in 1-3
working days after receiving your orders. Delivery time may differ from different purchasing way or
location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with
normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance
and extra fees will be charged.
Datasheet & COA
Please contact us to get it.
Description
This recombinant human CD19 protein is expressed in mammalian cells and features an amino acid sequence corresponding to the region 20-291aa of the B-lymphocyte antigen CD19 (CD19). The product has a C-terminal hFc-tag and is provided as a lyophilized powder, ready for reconstitution in sterile water or buffer before use. The purity of the protein is greater than 80%, as determined by SDS-PAGE, while the endotoxin level is less than 1.0 EU/µg, as measured by the LAL method. The ED50, determined by its ability to bind CD19 in a functional ELISA, is less than 20 µg/ml, making it suitable for various research applications in the field of immunology.
B-lymphocyte antigen CD19 (CD19) is a cell surface protein primarily expressed on B cells and is crucial for B-cell development and function. CD19 is involved in various aspects of B-cell activation, differentiation, and regulation, making it an essential molecule for the immune system and an attractive target for therapeutic interventions.