CD69

CD69, also known as "Cell Adhesion Molecule 69," is an immune cell surface molecule that belongs to the C-type cell adhesion molecule family. Its molecular structure includes an extracellular region, a transmembrane region, and an intracellular region. The extracellular region can interact with other cell surface molecules or extracellular matrix components, thereby participating in cell adhesion and signal transduction. CD69 is primarily expressed on the surface of activated immune cells, such as T lymphocytes, B lymphocytes, natural killer (NK) cells, and certain tissue macrophages. Upon external stimulation, such as antigenic stimulation, CD69 is rapidly upregulated on the cell surface, indicating cell activation and response. In the activation processes of T cells and B cells, CD69 expression can influence cell proliferation, differentiation, and cell death. CD69 expression on activated immune cells may play a role in cell migration. It can impact cell adhesion and migration capabilities, aiding immune cells in locating and targeting sites of infection or inflammation within the body. CD69 also plays a significant role in inflammation and immune responses. It participates in regulating inflammatory reactions and the chemotaxis and migration of immune cells. The function of CD69 is closely associated with tissue immune regulation and immune tolerance processes. Research on CD69 is crucial for gaining a deeper understanding of the mechanisms underlying immune cell activation, migration, and regulation. It may provide potential therapeutic targets for immune therapy and disease treatment.

More Interesting read related CD69:a Classical Early Marker of Lymphocyte Activation, a Pivotal Regulator of Hematologic Diseases and Autoimmune Disorders!

Popular Product

● CD69 Recombinant Monoclonal Antibody CSB-RA004952MA1HU

Validated Data

ELISA

The Binding Activity of Human CD69 with Anti-CD69 Recombinant Antibody

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD69 (CSB-MP004952HU) at 2 μg/mL can bind Anti-CD69 recombinant antibody , the EC₅₀ is 23.17-26.04 ng/mL

● Recombinant Human Early activation antigen CD69(CD69),partial (Active) CSB-MP004952HU

Validated Data

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel

ELISA

Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CD69 at 2μg/mL can bind Anti-CD69 recombinant antibody (CSB-RA004952MA1HU)， the EC₅₀ is 23.17-26.04 ng/mL.