CISH

The gene CISH encodes for the protein Cytokine Inducible SH2 Containing Protein, also known as CISH. This protein plays a crucial role in inhibiting T cell activation via PLC-γ1 regulation, acting as a potent checkpoint in CD8+ T cells. It is involved in the CISH signaling pathway, which is pertinent to various diseases, including bacteremia and malaria. Research in the field of CISH has led to the development of potential therapeutic targets, with ongoing studies exploring the use of drugs that modulate CISH function for treatment of these conditions.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CISH Antibody (CSB-PA885721ESR1HU)

Validated Data

Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA885721ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA885721ESR1HU at dilution of 1:100

The following CISH reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CISH Antibodies

CISH Proteins

CISH Antibodies

CISH Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA885721ESR1HU	CISH Antibody	Human	ELISA, IHC

CISH Proteins

CISH Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP005445RA CSB-EP005445RA CSB-BP005445RA CSB-MP005445RA CSB-EP005445RA-B	Recombinant Rat Cytokine-inducible SH2-containing protein (Cish)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CISH Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP642236BO CSB-EP642236BO CSB-BP642236BO CSB-MP642236BO CSB-EP642236BO-B	Recombinant Bovine Cytokine-inducible SH2-containing protein (CISH)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CISH Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP720292MO CSB-EP720292MO CSB-BP720292MO CSB-MP720292MO CSB-EP720292MO-B	Recombinant Mouse Cytokine-inducible SH2-containing protein (Cish)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CISH Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP868714CH CSB-EP868714CH CSB-BP868714CH CSB-MP868714CH CSB-EP868714CH-B	Recombinant Chicken Cytokine-inducible SH2-containing protein (CISH)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CISH Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP885721HU CSB-BP885721HU CSB-MP885721HU CSB-EP885721HU-B	Recombinant Human Cytokine-inducible SH2-containing protein (CISH)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP885721HU	Recombinant Human Cytokine-inducible SH2-containing protein (CISH)	E.coli

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CISH

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