Dsg3 (Desmoglein 3) belongs to the cell adhesion protein family and is a cell surface receptor. It possesses multiple extracellular glycosylation sites that allow it to interact with other cell adhesion proteins, thereby forming stable connections between cells. The structure of Dsg3 enables its participation in cell-cell adhesion, maintaining tissue integrity. Dsg3 primarily functions in epithelial cells, especially in skin and mucosal tissues. Its main role is to maintain adhesion and connections between epithelial cells.
Dsg3, through interactions with other cell adhesion proteins like Dsg1 and Dsc2/3, forms structures known as desmosomes, contributing to cell interlocking and tissue integrity. Loss of Dsg3 or abnormalities in its function can lead to certain skin and mucosal diseases, such as Pemphigus Vulgaris. Research on Dsg3 is critical for understanding the development and stability of skin and mucosal tissues.
● Recombinant Human Desmoglein-3(DSG3),partial (Active) CSB-BP007205HUc7
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human DSG3 at 2 μg/mL can bind Anti-DSG3 recombinant antibody (CSB-RA007205A0HU), the EC50 is 4.552-5.720 ng/mL.
● Recombinant Mouse Desmoglein-3(Dsg3),partial (Active) CSB-MP007205MOd7
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Dsg3 at 5 μg/ml can bind Anti-DSG3 recombinant antibody (CSB-RA007205A0HU), the EC50 is 2.624-3.182 μg/ml.
The following DSG3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
DSG3 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA007205LD01HU | DSG3 Antibody, Biotin conjugated |
Human | ELISA |
CSB-PA007205LC01HU | DSG3 Antibody, FITC conjugated |
Human | |
CSB-PA007205LB01HU | DSG3 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA007205LA01HU | DSG3 Antibody |
Human | ELISA, IHC, IF |
CSB-PA007205YA01HU | DSG3 Antibody |
Human, Mouse | ELISA, WB |
CSB-PA007205YB01HU | DSG3 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA007205YC01HU | DSG3 Antibody, FITC conjugated |
Human | |
CSB-PA007205YD01HU | DSG3 Antibody, Biotin conjugated |
Human | ELISA |
CSB-RA007205A0HU | DSG3 Recombinant Monoclonal Antibody |
Human, Mouse | ELISA |
DSG3 Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA007205LA01MO | Dsg3 Antibody |
Mouse | ELISA |
CSB-PA007205LB01MO | Dsg3 Antibody, HRP conjugated |
Mouse | ELISA |
CSB-PA007205ZA01MO | Dsg3 Antibody |
Mus musculus | ELISA, WB (ensure identification of antigen) |
DSG3 Proteins for Homo sapiens (Human)
DSG3 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP007205MO | Recombinant Mouse Desmoglein-3 (Dsg3), partial |
Yeast |
CSB-EP007205MO | Recombinant Mouse Desmoglein-3 (Dsg3), partial |
E.coli |
CSB-MP007205MO CSB-EP007205MO-B |
Recombinant Mouse Desmoglein-3 (Dsg3) |
Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP007205MOb0 | Recombinant Mouse Desmoglein-3 (Dsg3), partial |
E.coli |
CSB-BP007205MO | Recombinant Mouse Desmoglein-3 (Dsg3), partial |
Baculovirus |
CSB-EP007205MOe1 | Recombinant Mouse Desmoglein-3 (Dsg3), partial |
E.coli |
CSB-BP007205MOb0 | Recombinant Mouse Desmoglein-3 (Dsg3), partial |
Baculovirus |
CSB-MP007205MOd7 | Recombinant Mouse Desmoglein-3 (Dsg3), partial (Active) |
Mammalian cell |
CSB-BP007205MOd9 | Recombinant Mouse Desmoglein-3 (Dsg3), partial |
Baculovirus |
CSB-BP007205MOc7 | Recombinant Mouse Desmoglein-3 (Dsg3), partial |
Baculovirus |
CSB-BP007205MOk8 | Recombinant Mouse Desmoglein-3 (Dsg3), partial |
Baculovirus |
DSG3 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
Code | Product Name | Source |
---|---|---|
CSB-YP773566DO CSB-EP773566DO CSB-BP773566DO CSB-MP773566DO CSB-EP773566DO-B |
Recombinant Dog Desmoglein-3 (DSG3), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
DSG3 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL007205HU | Human Desmoglein-3(DSG3) ELISA kit |
serum, plasma, tissue homogenates | 7 pg/mL |