FGF23, or fibroblast growth factor 23, is a member of the fibroblast growth factor family. It is also known as FGF-23. FGF23 mainly acts on the kidneys, regulating phosphate and vitamin D metabolism through the Klotho-FGFR complex, thereby maintaining the body's phosphate and calcium balance. The signal pathway mainly involves the FGF receptor signaling pathway.
Abnormal FGF23 expression is associated with a variety of diseases, such as chronic kidney disease - mineral and bone disorder (CKD - MBD), tumor - induced osteomalacia. Currently, in drug development, targeting FGF23 and its associated signaling pathways is a potential therapeutic strategy for these related diseases, and some drugs are in different stages of research.
Recombinant Human Fibroblast growth factor 23 (FGF23), partial (CSB-EP008629HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Human fibroblast growth factor-23,FGF-23 ELISA Kit (CSB-E10113h)
Validated Data
Code: CSB-E10113h
Size: 96T,5×96T,10×96T
Sensitivity: 0.78 pg/mL
Detection Range: 3.12 pg/mL-200 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following FGF23 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
FGF23 Antibodies for Rattus norvegicus (Rat)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA008629LA01RA | Fgf23 Antibody | Rat | ELISA, WB |
CSB-PA008629LB01RA | Fgf23 Antibody, HRP conjugated | Rat | ELISA |
CSB-PA008629LD01RA | Fgf23 Antibody, Biotin conjugated | Rat | ELISA |
FGF23 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA163892 | FGF23 Antibody | Human,Mouse | ELISA,WB,IF |
CSB-PA005032 | FGF23 Antibody | Human | WB, ELISA |
CSB-PA060188 | FGF23 Antibody | Human,Mouse,Rat | WB, IF, ELISA |
CSB-PA13919B0Rb | FGF23 Antibody, HRP conjugated | Human | ELISA |
CSB-PA13919C0Rb | FGF23 Antibody, FITC conjugated | Human | |
CSB-PA13919D0Rb | FGF23 Antibody, Biotin conjugated | Human | ELISA |
CSB-PA13919A0Rb | FGF23 Antibody | Human | ELISA, IF |
FGF23 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-EP008629RA | Recombinant Rat Fibroblast growth factor 23 (Fgf23) | E.coli |
CSB-YP008629RA | Recombinant Rat Fibroblast growth factor 23 (Fgf23) | Yeast |
CSB-BP008629RA CSB-MP008629RA CSB-EP008629RA-B |
Recombinant Rat Fibroblast growth factor 23 (Fgf23) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGF23 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP008629MO CSB-EP008629MO CSB-BP008629MO CSB-MP008629MO CSB-EP008629MO-B |
Recombinant Mouse Fibroblast growth factor 23 (Fgf23) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGF23 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP008629HU CSB-BP008629HU CSB-MP008629HU CSB-EP008629HU-B |
Recombinant Human Fibroblast growth factor 23 (FGF23) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP002481HU | Recombinant Human Fibroblast growth factor 23 protein (FGF23) (Active) | E.coli |
CSB-EP008629HU | Recombinant Human Fibroblast growth factor 23 (FGF23), partial | E.coli |
FGF23 Proteins for Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)
Code | Product Name | Source |
---|---|---|
CSB-YP008629TCA CSB-EP008629TCA CSB-BP008629TCA CSB-MP008629TCA CSB-EP008629TCA-B |
Recombinant Tetraodon nigroviridis Fibroblast growth factor 23 (fgf23) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGF23 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E10113h | Human fibroblast growth factor-23,FGF-23 ELISA Kit | serum, cell culture supernates, urine, tissue homogenates | 0.78 pg/mL |
FGF23 ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL008629MO | Mouse Fibroblast growth factor 23(FGF23) ELISA kit | serum, plasma, tissue homogenates | 5.86 pg/mL |
FGF23 ELISA Kit for Rattus norvegicus (Rat)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E12170r | Rat fibroblast growth factor 23 (FGF23) ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 0.39 pg/mL |
CSB-E12170r(1) | Rat fibroblast growth factor 23 (FGF23) ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 3.9 ng/mL |