IRF3

Interferon regulatory factor 3 is a protein in humans that is encoded by IRF3 gene. Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and late phases of the IFNA/B gene induction. Found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, is phosphorylated by IKBKE and TBK1 kinases.

IRF3 Antibodies

IRF3 Antibodies for Homo sapiens (Human)

IRF3 Antibodies for Human

IRF3 Antibodies for Mouse

IRF3 Proteins

IRF3 Proteins for Mus musculus (Mouse)

IRF3 Proteins for Sus scrofa (Pig)

IRF3 Proteins for Gallus gallus (Chicken)

IRF3 Proteins for Homo sapiens (Human)

IRF3 Proteins for Bos taurus (Bovine)

IRF3 cDNA for Homo sapiens (Human)

Code Product Name Vector Accession NO.
CSB-CL011818HU1 IRF3 pUC NM_001197124.1
CSB-CL011818HU2 IRF3 pUC NM_001571.5

IRF3 cDNA for Sus scrofa (Pig)

Code Product Name Vector Accession NO.
CSB-CL011818PI IRF3 pUC NM_213770.1

IRF3 cDNA for Gallus gallus (Chicken)

Code Product Name Vector Accession NO.
CSB-CL011818CH IRF7 pUC NM_205372.1

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