Musk (Muscle-Specific Kinase) is a receptor for muscle-specific tyrosine kinase, involved in the transmission of nerve impulses to muscles. As a transmembrane protein, Musk contains a kinase domain. It predominantly resides on the postsynaptic membrane of the neuromuscular junction, binding to the neurotransmitter acetylcholine released by neurons and transmitting signals within muscle cells. The primary function of Musk protein is to facilitate the transmission of nerve impulses at the neuromuscular junction. When acetylcholine is released at the neuromuscular junction, Musk receptors activate, initiating a series of signal transduction processes that ultimately lead to muscle contraction. Research on Musk protein aids in a deeper understanding of neuromuscular junction functionality and helps comprehend and treat Musk-related conditions, such as specific types of Myasthenia Gravis. By delving into Musk's role in neuromuscular connections, crucial insights are provided for the development of related therapeutic approaches.
Recombinant Mouse Muscle, skeletal receptor tyrosine-protein kinase (Musk),partial
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP730715MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Musk.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP730715MO could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Musk.
The following MUSK reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MUSK Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA204567 | Phospho-MUSK (Tyr755) Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA010281 | Phospho-MUSK (Y755) Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA579873 | MUSK Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA989887 | MUSK Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA015241ZA01HU | MUSK Antibody |
Homo sapiens | ELISA, WB (ensure identification of antigen) |
MUSK Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA730715ZA01MO | Musk Antibody |
Mus musculus | ELISA, WB (ensure identification of antigen) |
MUSK Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP015241HU | Recombinant Human Muscle, skeletal receptor tyrosine-protein kinase (MUSK), partial |
Yeast |
CSB-EP015241HU | Recombinant Human Muscle, skeletal receptor tyrosine-protein kinase (MUSK), partial |
E.coli |
CSB-BP015241HU CSB-MP015241HU CSB-EP015241HU-B |
Recombinant Human Muscle, skeletal receptor tyrosine-protein kinase (MUSK), partial |
Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-CF015241HU | Recombinant Human Muscle, skeletal receptor tyrosine-protein kinase (MUSK), partial (Active) |
in vitro E.coli expression system |
CSB-CF015241HUb0 | Recombinant Human Muscle, skeletal receptor tyrosine-protein kinase (MUSK), partial |
in vitro E.coli expression system |
MUSK Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP730715MO CSB-BP730715MO CSB-MP730715MO CSB-EP730715MO-B |
Recombinant Mouse Muscle, skeletal receptor tyrosine-protein kinase (Musk), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP730715MO | Recombinant Mouse Muscle, skeletal receptor tyrosine-protein kinase (Musk),Partial |
E.coli |
MUSK Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP733845RA CSB-BP733845RA CSB-MP733845RA CSB-EP733845RA-B |
Recombinant Rat Muscle, skeletal receptor tyrosine protein kinase (Musk), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP733845RA | Recombinant Rat Muscle, skeletal receptor tyrosine protein kinase (Musk), partial |
E.coli |
MUSK Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP805845CH CSB-EP805845CH CSB-BP805845CH CSB-MP805845CH CSB-EP805845CH-B |
Recombinant Chicken Muscle, skeletal receptor tyrosine protein kinase (MUSK), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MUSK ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E15804h | Human Muscle Skeletal Receptor Tyrosine Kinase (MUSK) ELISA Kit |
serum, plasma, tissue homogenates | 0.39 pg/mL |