Merlin is a protein in humans that is encoded by NF2 gene. Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.
The following NF2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
NF2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA015741GA01HU | NF2 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA149148 | Phospho-NF2 (Ser518) Antibody |
Human,Mouse,Rat | ELISA,WB,IF |
CSB-PA779103 | NF2 (Ab-518) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA249373 | NF2 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA003420 | NF2 Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA020074 | Phospho-NF2 (S518) Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA020075 | Phospho-NF2 (S10) Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA020077 | NF2 Antibody |
Human,Mouse,Rat | WB, ELISA |
CSB-PA015741LA01HU | NF2 Antibody |
Human, Mouse | ELISA, WB, IHC, IF |
CSB-PA015741LB01HU | NF2 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA015741LC01HU | NF2 Antibody, FITC conjugated |
Human | |
CSB-PA015741LD01HU | NF2 Antibody, Biotin conjugated |
Human | ELISA |
NF2 Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA015741ZA01MO | Nf2 Antibody |
Mus musculus | ELISA, WB (ensure identification of antigen) |
NF2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP015741HU CSB-BP015741HU CSB-MP015741HU CSB-EP015741HU-B |
Recombinant Human Merlin (NF2) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP015741HU | Recombinant Human Merlin (NF2) |
E.coli |
NF2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP015741MO1 CSB-BP015741MO1 CSB-MP015741MO1 CSB-EP015741MO1-B |
Recombinant Mouse Merlin (Nf2), partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP015741MO1 | Recombinant Mouse Merlin (Nf2), partial |
E.coli |
NF2 Proteins for Papio anubis (Olive baboon)
Code | Product Name | Source |
---|---|---|
CSB-YP015741ERI CSB-EP015741ERI CSB-BP015741ERI CSB-MP015741ERI CSB-EP015741ERI-B |
Recombinant Papio anubis Merlin (NF2), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NF2 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP726923RA CSB-EP726923RA CSB-BP726923RA CSB-MP726923RA CSB-EP726923RA-B |
Recombinant Rat Merlin (Nf2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |