NF2 Research Reagents

Merlin is a protein in humans that is encoded by NF2 gene. Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.

The following NF2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

NF2 Antibodies

NF2 Antibodies for Homo sapiens (Human)

NF2 Antibodies for Mus musculus (Mouse)

NF2 Proteins

NF2 Proteins for Homo sapiens (Human)

NF2 Proteins for Mus musculus (Mouse)

NF2 Proteins for Papio anubis (Olive baboon)

NF2 Proteins for Rattus norvegicus (Rat)

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