Tumor necrosis factor receptor superfamily member 14 (TNFRSF14),also known as herpesvirus entry mediator (HVEM), is a receptor for BTLA, TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. The protein encoded by this gene is a member of the TNF-receptor superfamily. The cytoplasmic region of this receptor was found to bind to several TNF receptor associated factor (TRAF) family members, which may mediate the signal transduction pathways that activate the immune response. it is involved in lymphocyte activation, and plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.
TNFRSF14 Antibodies for Homo sapiens (Human)
|Code||Product Name||Species Reactivity||Application|
TNFRSF14 Proteins for Homo sapiens (Human)
In Vivo Biotinylation in E.coli
TNFRSF14 ELISA Kit for Homo sapiens (Human)
|Code||Product Name||Sample Types||Sensitivity|
|CSB-EL023973HU||serum, plasma, tissue homogenates||3.9 pg/mL|