Transferrin receptor protein 1 is a protein in humans that is encoded by TFRC gene. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. Positively regulates T and B cell proliferation through iron uptake

Tfrc Antibodies

Tfrc Antibodies for Homo sapiens (Human)

Tfrc Proteins

Tfrc Proteins for Equus caballus (Horse)

Tfrc Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Tfrc Proteins for Mus musculus (Mouse)

Tfrc Proteins for Sus scrofa (Pig)

Tfrc Proteins for Gallus gallus (Chicken)

Tfrc Proteins for Rattus norvegicus (Rat)

Tfrc Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Tfrc Proteins for Felis catus (Cat) (Felis silvestris catus)

Tfrc Proteins for Mus musculus(Mouse)

Tfrc ELISA Kit

Tfrc ELISA Kit for Mus musculus (Mouse)

Tfrc ELISA Kit for Homo sapiens (Human)


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