Greater than 90% as determined by SDS-PAGE.
Clade E; Endothelial plasminogen activator inhibitor; Nexin ; Nexin plasminogen activator inhibitor type 1; PAI 1; PAI; PAI-1; PAI1_HUMAN; PLANH1; Plasminogen activator inhibitor 1; Plasminogen activator inhibitor type 1; Serine (or cysteine) proteinase inhibitor ; Serine (or cysteine) proteinase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1; Serine proteinase inhibitor clade E member 1; serpin; Serpin E1; Serpin peptidase inhibitor clade E (nexin plasminogen activator inhibitor type 1) member 1; Serpin peptidase inhibitor clade E; Serpine 1; SERPINE1
Homo sapiens (Human)
Target Protein Sequence
Note: The complete sequence including tag
sequence, target protein sequence and linker sequence could be provided upon request.
Liquid or Lyophilized powder
Note: We will preferentially ship the format that
we have in stock, however, if you have any special requirement for the format, please remark your
requirement when placing the order, we will prepare according to your demand.
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the
glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer,
6% Trehalose, pH 8.0.
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized
form is 12 months at -20°C/-80°C.
3-7 business days
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.
The region for expressing recombinant Human SERPINE1 contains amino acids 24-401. The theoretical molecular weight of the SERPINE1 protein is 46.7 kDa. This SERPINE1 protein is produced using e.coli expression system. The SERPINE1 coding gene included the N-terminal 6xHis tag, which simplifies the detection and purification processes of the recombinant SERPINE1 protein in following stages of expression and purification.
Plasminogen activator inhibitor 1 (SERPINE1) is a member of the serine protease inhibitor (serpin) family and plays a crucial role in the regulation of fibrinolysis. SERPINE1 inhibits tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA), thus controlling the conversion of plasminogen to plasmin, a key enzyme in the dissolution of blood clots. Beyond its role in fibrinolysis, SERPINE1 is involved in various physiological and pathological processes, including tissue remodeling, inflammation, and cell migration. Dysregulation of SERPINE1 is implicated in conditions such as thrombosis, cardiovascular diseases, and cancer. Research on SERPINE1 explores its potential as a therapeutic target in diseases associated with altered fibrinolytic activity.