About Thyroid Tumor, This Information You Must Know!The thyroid gland is part of the endocrine system and is a hormone-producing gland that regulates the body's functions. Thyroid cancer (TC), which occurs in thyroid cells, is the most common endocrine - related cancer, a...
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Mesothelin: A Rising Star of Cancer ImmunotherapyMesothelin, also known as MSLN, is a cell surface glycoprotein encoded by the MSLN gene. The MSLN gene encodes a precursor protein that is enzymatically decomposed into two products: megakaryocyte-potentiating factor (MP...
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OMA1-A Potential Cancer Therapy TargetThe mitochondria are double-membrane-bound organelles found in most eukaryotic organisms and are the main energizing organelles of cells. The most prominent roles of mitochondria are to produce the energy currency of the...
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EphA3-A Regulator of Cell Adhesion and MigrationReceptor tyrosine kinase (RTKs) is a type I transmembrane glycoprotein that regulates cell growth, differentiation and migration. The Eph receptor family (erythropoietin-producing human hepatocellular carcinoma) is the l...
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A Comprehensive Overview of Ovarian CancerOvarian cancer, as a gynecological malignancy, exerts a significant impact on women's health. Its highly invasive nature and the challenge of early detection pose a threat to the quality and longevity of women's lives. ...
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Growth Hormone - Not Only Promotes Height IncreaseGrowth hormone 1, also known as somatotropin, or growth hormone (GH). It is a member of the growth hormone/prolactin family. It is a single peptide chain protein hormone secreted by pituitary gland. The role of this horm...
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TROP2, An Important Target for Cancer ResearchTROP2 belongs to the TACSTD family and is a cell surface glycoprotein encoded by the TACSTD2 gene. It is also known as tumor-associated calcium signal transducer 2 (TACSTD2), epidermal glycoprotein 1 (EGP-1), and gastroi...
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PD-1/PD-L1, What a Powerful Immune CheckpointImmune checkpoint therapy, mainly including anti-CTLA-4 therapy and anti-PD-1/PD-L1 therapy, which targets regulatory pathways in T cells to enhance antitumor immune responses by blocking the inhibitory signals of the im...
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CD31- A Complex Function MoleculeAt the 2015 ASCO Annual Meeting, the team of Michael J. Birrer, MD, et al. proposed that CD31 is a potential biomarker for bevacizumab in ovarian cancer. Because the effect of bevacizumab on progression-free survival (PF...
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CD14, A Membrane Receptor for Bacterial LipopolysaccharidesCD14 (cluster of differentiation 14), formerly known as MY23 antigen, is a surface antigen and is a member of the cell surface glycoprotein family. The protein encoded by the CD14 gene is preferentially expressed in mono...
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