CD20 Monoclonal Antibodies Drugs: There is an Explosion of New mAbs Against CD20!On August 23, 2022, Sinocelltech Group Ltd. from China's NMPA has received marketing approval for its recombinant chimeric anti-CD20 monoclonal antibody--Ripertamab (SCT-400), to treat patients with CD20-positive diffuse...
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Get An Overview of His-TagIn analyzing the structure and function of recombinant proteins, the most important thing is to get pure recombinant proteins. Therefore, various methods have been explored to isolate high-purity recombinant proteins. Am...
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Nanoparticle platformIt is difficult for small molecular weight proteins to generate an immune response due to their small molecular weight. Although the fusion of large tags can enhance the immune response, the structure of the target prote...
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Protein Tyrosine Kinases: Anti-tumor Targets to be Explored UrgentlyIn 2001, the first kinase inhibitor imatinib was approved by the FDA and successfully marketed, representing an important breakthrough of kinase drugs in the field of molecular targeted cancer treatment. Recently, an art...
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Tuberculosis--A Resurgent As World Tuberculosis Day on March 24 approaches, I would like to take this opportunity to discuss tuberculosis, a major global public health threat that still persists. According to the World Health Organizati...
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SLC7A11: a New Potential Therapeutic Target via Induced Ferroptosis in Tumors!Lately, Cell (Impact Factor=66.850) released "Ferroptosis" review to mark the ten-year anniversary of the discovery of ferroptosis [1]! The article focuses on the key regulators of this form of cell death, which promise ...
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A Review of WFDC8 AntibodyProduct Name: WFDC8 antibody Code:  CSB-PA818226LA01HU I am Dr. Ferran Barrachina, currently a postdoctoral fellow at the Massachusetts General Hospital and Harvard Medical School in Boston (United States). My r...
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A Review of A Human NGAL ELISA KitProduct Name: Human neutrophil gelatinase-associated lipocalin, NGAL ELISA Kit Code: CSB-E09408h We used the Elisa kit CSB-E09408h for the assessment of NGAL concentration in urine samples of children, adults and chr...
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CLDN4: A Potential Prognostic Indicator and Therapeutic Target in Tumors！Presently, a paper entitled "TGF-β induces GBM mesenchymal transition through upregulation of CLDN4 and nuclear translocation to activate TNF-α/NF-κB signal pathway" was published on Cell Death & Disease. The stud...
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Intestinal Mucosal Barrier Bodyguard --ALPiThe intestinal mucosal barrier is a critical component of the gastrointestinal tract, serving as the front-line defense against pathogens, toxins, and dietary antigens. Its integrity is paramount to health [1]. Inversely...
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