CTSK

CTSK, a cysteine protease mainly released by osteoclasts, plays a critical role in the breakdown of collagen in bone resorption. Beyond osteoclasts, CTSK is found in cells like chondrocytes and certain tumors. It's central to the degradation of bone matrix, a process regulated by factors including pH and inhibitors. Vital for bone remodeling and mineralization, CTSK's dysfunction or overactivity is associated with bone disorders and cancer progression, potentially promoting tumor growth and spread. Its expression levels can predict tumor aggressiveness and patient outcomes, positioning CTSK as a therapeutic target for osteoporosis and some cancers.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CTSK Antibody (CSB-PA006192ESR1HU)

Validated Data

Western blot
All lanes: CTSK antibody at 8μg/ml
Lane 1: MCF-7 whole cell lysate
Lane 2: Rat brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 37 kDa
Observed band size: 37 kDa

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA006192ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA006192ESR1HU at dilution of 1:100

Human Cathepsin K,cath-K ELISA Kit (CSB-E09438h)

Validated Data

Code: CSB-E09438h

Size: 96T,5×96T,10×96T

Sensitivity: 1.95 pg/mL

Detection Range: 7.8 pg/mL-500 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following CTSK reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

CTSK Antibodies

CTSK Proteins

CTSK ELISA Kits

CTSK Antibodies

CTSK Antibodies for Rattus norvegicus (Rat)

Code	Product Name	Species Reactivity	Application
CSB-PA006192LA01RA	Ctsk Antibody	Rat	ELISA, IHC

CTSK Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA006192GA01HU	CTSK Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA15119A0Rb	CTSK Antibody	Human	ELISA
CSB-PA006192ESR1HU	CTSK Antibody	Human, Rat	ELISA, WB, IHC
CSB-PA039740	CTSK Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA145433	CTSK Antibody	Human,Mouse,Rat	ELISA,IHC

CTSK Antibodies for Mus musculus (Mouse)

Code	Product Name	Species Reactivity	Application
CSB-PA006192ZA01MO	Ctsk Antibody	Mus musculus	ELISA, WB (ensure identification of antigen)

CTSK Antibodies for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Species Reactivity	Application
CSB-PA006192ZA01MOV	CTSK Antibody	Macaca fascicularis	ELISA, WB (ensure identification of antigen)

CTSK Antibodies for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Species Reactivity	Application
CSB-PA006192ZA01DO	CTSK Antibody	Canis lupus familiaris	ELISA, WB (ensure identification of antigen)

CTSK Antibodies for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Species Reactivity	Application
CSB-PA006192ZA01RB	CTSK Antibody	Oryctolagus cuniculus	ELISA, WB (ensure identification of antigen)

CTSK Proteins

CTSK Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP006192HU	Recombinant Human Cathepsin K (CTSK)	Yeast
CSB-BP006192HU CSB-MP006192HU CSB-EP006192HU-B	Recombinant Human Cathepsin K (CTSK)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006192HU	Recombinant Human Cathepsin K (CTSK)	E.coli

CTSK Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP006192RB CSB-BP006192RB CSB-MP006192RB CSB-EP006192RB-B	Recombinant Rabbit Cathepsin K (CTSK)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006192RB	Recombinant Rabbit Cathepsin K (Ctsk)	E.coli

CTSK Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP006192MO CSB-BP006192MO CSB-MP006192MO CSB-EP006192MO-B	Recombinant Mouse Cathepsin K (Ctsk)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006192MO	Recombinant Mouse Cathepsin K (Ctsk)	E.coli

CTSK Proteins for Macaca mulatta (Rhesus macaque)

Code	Product Name	Source
CSB-YP006192MOW CSB-EP006192MOW CSB-BP006192MOW CSB-MP006192MOW CSB-EP006192MOW-B	Recombinant Macaca mulatta (Rhesus macaque) Cathepsin K (CTSK)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSK Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP006192RA CSB-BP006192RA CSB-MP006192RA CSB-EP006192RA-B	Recombinant Rat Cathepsin K (Ctsk)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006192RA	Recombinant Rat Cathepsin K (Ctsk)	E.coli

CTSK Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP006192MOV CSB-BP006192MOV CSB-MP006192MOV CSB-EP006192MOV-B	Recombinant Macaca fascicularis Cathepsin K (CTSK)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006192MOV	Recombinant Macaca fascicularis Cathepsin K (CTSK)	E.coli

CTSK Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP006192CH CSB-EP006192CH CSB-BP006192CH CSB-MP006192CH CSB-EP006192CH-B	Recombinant Chicken Cathepsin K (CTSK)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSK Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP006192PI CSB-EP006192PI CSB-BP006192PI CSB-MP006192PI CSB-EP006192PI-B	Recombinant Pig Cathepsin K (CTSK)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

CTSK Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP006192DO CSB-BP006192DO CSB-MP006192DO CSB-EP006192DO-B	Recombinant Dog Cathepsin K (CTSK)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP006192DO	Recombinant Dog Cathepsin K (CTSK)	E.coli

CTSK Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP006192BO CSB-EP006192BO CSB-BP006192BO CSB-MP006192BO CSB-EP006192BO-B	Recombinant Bovine Cathepsin K (CTSK)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli