HAVCR2, also known as TIM-3 (T-cell immunoglobulin domain and mucin domain-3), is a transmembrane protein predominantly expressed on T cells. It interacts with ligands such as phosphatase CD244 and phosphatidylserine (PS), modulating immune responses and serving as an inhibitory receptor in T cell activity regulation. HAVCR2's role extends to autoimmune diseases, infectious diseases, tumor immune surveillance, and immune escape, marking it as an inhibitory molecule in adaptive immunity. Its expression changes in tumors suggest potential as a target in immunotherapy research.
Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial (CSB-EP010145HU)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
HAVCR2 Recombinant Monoclonal Antibody (CSB-RA010145MA1HU)
Validated Data
Immunofluorescence staining of Hela cell with CSB-RA010145MA1HU at 1:150, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Human IgG(H+L).
Human Hepatitis A virus cellular receptor 2(HAVCR2) ELISA kit (CSB-EL010145HU)
Validated Data
Code: CSB-EL010145HU
Size: 96T,5×96T,10×96T
Sensitivity: 11.75 pg/mL
Detection Range: 47 pg/mL-3000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
The following HAVCR2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
HAVCR2 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA010145GA01HU | HAVCR2 Antibody | Human | ELISA,WB |
CSB-PA010145LC01HU | HAVCR2 Antibody, FITC conjugated | Human | |
CSB-PA010145LA01HU | HAVCR2 Antibody | Human | ELISA, IF |
CSB-PA010145LD01HU | HAVCR2 Antibody, Biotin conjugated | Human | ELISA |
CSB-PA010145LB01HU | HAVCR2 Antibody, HRP conjugated | Human | ELISA |
CSB-RA010145MA1HU | HAVCR2 Recombinant Monoclonal Antibody | Human | ELISA, IF |
HAVCR2 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP010145RA CSB-EP010145RA CSB-BP010145RA CSB-MP010145RA CSB-EP010145RA-B |
Recombinant Rat Hepatitis A virus cellular receptor 2 homolog (Havcr2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HAVCR2 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP010145HU | Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial | Yeast |
CSB-EP010145HU | Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial | E.coli |
CSB-BP010145HU CSB-EP010145HU-B |
Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2) | Baculovirus In Vivo Biotinylation in E.coli |
CSB-AP005281HU | Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial (Active) | Mammalian cell |
CSB-AP005291HU | Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial (Active) | Mammalian cell |
CSB-MP010145HU1 | Recombinant Human Hepatitis A virus cellular receptor 2 (HAVCR2), partial | Mammalian cell |
HAVCR2 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP840881MO CSB-EP840881MO CSB-BP840881MO CSB-MP840881MO CSB-EP840881MO-B |
Recombinant Mouse Hepatitis A virus cellular receptor 2 homolog (Havcr2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-AP005341MO | Recombinant Mouse Hepatitis A virus cellular receptor 2 homolog (Havcr2), partial (Active) | Mammalian cell |
HAVCR2 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL010145HU | Human Hepatitis A virus cellular receptor 2(HAVCR2) ELISA kit | serum, plasma, tissue homogenates | 11.75 pg/mL |