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NADPH oxidase 4 is a protein in humans that is encoded by NOX4 gene. Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity.
The following Nox4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
Nox4 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA015961GA01HU | NOX4 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA777165 | NOX4 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA034129 | NOX4 Antibody |
Human,Mouse,Rat | ELISA,IHC |
| CSB-PA015961LA01HU | NOX4 Antibody |
Human | ELISA, IHC, IF |
| CSB-PA015961LB01HU | NOX4 Antibody, HRP conjugated |
Human | ELISA |
| CSB-PA015961LC01HU | NOX4 Antibody, FITC conjugated |
Human | |
| CSB-PA015961LD01HU | NOX4 Antibody, Biotin conjugated |
Human | ELISA |
| CSB-PA015961ZA01HU | NOX4 Antibody |
Homo sapiens | ELISA, WB (ensure identification of antigen) |
Nox4 Antibodies for Rattus norvegicus (Rat)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA015961LA01RA | Nox4 Antibody |
Rat, Human | ELISA, WB |
Nox4 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP015961MO | Recombinant Mouse NADPH oxidase 4(Nox4),partial,Yeast |
Yeast |
| CSB-EP015961MO CSB-BP015961MO CSB-MP015961MO CSB-EP015961MO-B |
Recombinant Mouse NADPH oxidase 4(Nox4),partial |
E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Nox4 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP015961RA | Recombinant Rat NADPH oxidase 4(Nox4),partial |
Yeast |
| CSB-CF015961RA(A4) | Recombinant Rat NADPH oxidase 4(Nox4) |
in vitro E.coli expression system |
| CSB-EP015961RA | Recombinant Rat NADPH oxidase 4(Nox4),partial |
E.coli |
| CSB-BP015961RA CSB-MP015961RA CSB-EP015961RA-B |
Recombinant Rat NADPH oxidase 4,partial |
Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Nox4 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-CF015961HU | Recombinant Human NADPH oxidase 4(NOX4) |
in vitro E.coli expression system |
| CSB-EP015961HU1 | Recombinant Human NADPH oxidase 4(NOX4),partial |
E.coli |
| CSB-YP015961HU1 CSB-BP015961HU1 CSB-MP015961HU1 CSB-EP015961HU1-B |
Recombinant Human NADPH oxidase 4(NOX4),partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-MP015961HU | Recombinant Human NADPH oxidase 4(NOX4)-VLPs |
Mammalian cell |
Nox4 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
| Code | Product Name | Source |
|---|---|---|
| CSB-CF015961PYX | Recombinant Pongo abelii NADPH oxidase 4(NOX4) |
in vitro E.coli expression system |
| CSB-YP015961PYX1 CSB-EP015961PYX1 CSB-BP015961PYX1 CSB-MP015961PYX1 CSB-EP015961PYX1-B |
Recombinant Pongo abelii NADPH oxidase 4(NOX4) ,partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-MP015961PYX | Recombinant Pongo abelii NADPH oxidase 4(NOX4)-VLPs |
Mammalian cell |
Nox4 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL015961HU | Human NADPH oxidase 4(NOX4) ELISA kit |
serum, plasma, tissue homogenates, cell lysates | 2.34 pg/mL |
