Nox4 Research Reagents

NADPH oxidase 4 is a protein in humans that is encoded by NOX4 gene. Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity.

The following Nox4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

Nox4 Antibodies

Nox4 Antibodies for Homo sapiens (Human)

Nox4 Antibodies for Rattus norvegicus (Rat)

Nox4 Proteins

Nox4 Proteins for Mus musculus (Mouse)

Nox4 Proteins for Rattus norvegicus (Rat)

Nox4 Proteins for Homo sapiens (Human)

Nox4 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Nox4 ELISA Kit

Nox4 ELISA Kit for Homo sapiens (Human)

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