Mothers against decapentaplegic homolog 2 is a protein in humans that is encoded by SMAD2 gene. Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

SMAD2 Antibodies

SMAD2 Antibodies for Homo sapiens (Human)

SMAD2 Antibodies for Human

SMAD2 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

SMAD2 Proteins

SMAD2 Proteins for Rattus norvegicus (Rat)

SMAD2 Proteins for Homo sapiens (Human)

SMAD2 Proteins for Bos taurus (Bovine)

SMAD2 Proteins for Mus musculus (Mouse)

SMAD2 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

SMAD2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

SMAD2 cDNA for Bos taurus (Bovine)

Code Product Name Vector Accession NO.
CSB-CL630205BO SMAD2 pUC NM_001046218.1

SMAD2 cDNA for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code Product Name Vector Accession NO.
CSB-CL735708PYX SMAD2 pUC NM_001132904.2


SMAD2 ELISA Kit for Homo sapiens (Human)


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