SMAD2

Mothers against decapentaplegic homolog 2 is a protein in humans that is encoded by SMAD2 gene. Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

SMAD2 Antibodies

SMAD2 Antibodies for Homo sapiens (Human)

Code Product Name Species Reactivity Application
CSB-PA021787GA01HU SMAD2 Antibody Human,Mouse,Rat ELISA,WB,IHC
CSB-PA783890 Phospho-SMAD2 (Ser467) Antibody Human,Mouse,Rat ELISA,WB
CSB-PA084599 Phospho-SMAD2 (Thr220) Antibody Human,Mouse,Rat ELISA,WB
CSB-PA047751 SMAD2 (Ab-467) Antibody Human,Mouse,Rat ELISA,WB,IF
CSB-PA093530 SMAD2 (Ab-220) Antibody Human,Mouse,Rat ELISA,WB,IHC
CSB-PA788461 Phospho-SMAD2 (Ser250) Antibody Human,Mouse,Rat ELISA,WB
CSB-PA139936 Phospho-SMAD2 (Ser465) Antibody Human,Mouse,Rat ELISA,WB
CSB-PA594584 SMAD2 (Ab-220) Antibody Human,Mouse,Rat ELISA,WB,IHC
CSB-PA981649 SMAD2 (Ab-465) Antibody Human,Mouse,Rat ELISA,WB
CSB-PA000675 Phospho-SMAD2 (S467) Antibody Human,Mouse,Rat WB,IHC,ELISA
CSB-PA004106 SMAD2 Antibody Human,Mouse,Rat WB,ELISA
CSB-PA004107 SMAD2 Antibody Human,Mouse,Rat WB,IHC,ELISA
CSB-PA004109 SMAD2 Antibody Human,Mouse,Rat WB,IHC,IF,ELISA
CSB-PA009933 Phospho-SMAD2 (S250) Antibody Human,Mouse,Rat WB,ELISA
CSB-PA009945 Phospho-SMAD2 (S465) Antibody Human,Mouse,Rat WB,IHC,ELISA
CSB-PA009946 Phospho-SMAD2 (T220) Antibody Human,Mouse,Rat IHC,IF,ELISA
CSB-PA009952 SMAD2 Antibody Human,Mouse,Rat WB,IHC,IF,ELISA
CSB-PA009953 SMAD2 Antibody Human,Mouse,Rat WB,ELISA
CSB-PA080253 SMAD2 Antibody Human WB
CSB-PA15557A0Rb SMAD2 Antibody Human, Mouse ELISA, WB, IHC, IF
CSB-PA15557B0Rb SMAD2 Antibody, HRP conjugated Human ELISA
CSB-PA15557C0Rb SMAD2 Antibody, FITC conjugated Human ELISA
CSB-PA15557D0Rb SMAD2 Antibody, Biotin conjugated Human ELISA
CSB-RA618017A250phHU Phospho-SMAD2 (S250) Antibody Human ELISA, WB
CSB-RA618017A255phHU Phospho-SMAD2 (S255) Antibody Human ELISA, IF

SMAD2 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code Product Name Species Reactivity Application
CSB-PA884853XA01DIL SMAD2 Antibody Danio rerio (Zebrafish) (Brachydanio rerio) ELISA, WB (ensure identification of antigen)

SMAD2 Proteins

SMAD2 Proteins for Rattus norvegicus (Rat)

Code Product Name Source
CSB-YP021787RA Recombinant Rat Mothers against decapentaplegic homolog 2(Smad2),Yeast Yeast
CSB-EP021787RA Recombinant Rat Mothers against decapentaplegic homolog 2(Smad2),Escherichia Coli E.coli
CSB-BP021787RA Recombinant Rat Mothers against decapentaplegic homolog 2(Smad2),Baculovirus Baculovirus
CSB-MP021787RA Recombinant Rat Mothers against decapentaplegic homolog 2(Smad2),Mammalian cell Mammalian cell

SMAD2 Proteins for Homo sapiens (Human)

Code Product Name Source
CSB-YP618017HU Recombinant Human Mothers against decapentaplegic homolog 2(SMAD2),Yeast Yeast
CSB-EP618017HU Recombinant Human Mothers against decapentaplegic homolog 2(SMAD2) E.coli
CSB-BP618017HU Recombinant Human Mothers against decapentaplegic homolog 2(SMAD2),Baculovirus Baculovirus
CSB-MP618017HU Recombinant Human Mothers against decapentaplegic homolog 2(SMAD2),Mammalian cell Mammalian cell
CSB-EP618017HUa2 Recombinant Human Mothers against decapentaplegic homolog 2(SMAD2) E.coli

SMAD2 Proteins for Bos taurus (Bovine)

Code Product Name Source
CSB-YP630205BO Recombinant Bovine Mothers against decapentaplegic homolog 2(SMAD2),Yeast Yeast
CSB-EP630205BO Recombinant Bovine Mothers against decapentaplegic homolog 2(SMAD2),Escherichia Coli E.coli
CSB-BP630205BO Recombinant Bovine Mothers against decapentaplegic homolog 2(SMAD2),Baculovirus Baculovirus
CSB-MP630205BO Recombinant Bovine Mothers against decapentaplegic homolog 2(SMAD2),Mammalian cell Mammalian cell

SMAD2 Proteins for Mus musculus (Mouse)

Code Product Name Source
CSB-YP733826MO Recombinant Mouse Mothers against decapentaplegic homolog 2(Smad2),Yeast Yeast
CSB-EP733826MO Recombinant Mouse Mothers against decapentaplegic homolog 2(Smad2),Escherichia Coli E.coli
CSB-BP733826MO Recombinant Mouse Mothers against decapentaplegic homolog 2(Smad2),Baculovirus Baculovirus
CSB-MP733826MO Recombinant Mouse Mothers against decapentaplegic homolog 2(Smad2),Mammalian cell Mammalian cell

SMAD2 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code Product Name Source
CSB-YP735708PYX Recombinant Pongo abelii Mothers against decapentaplegic homolog 2(SMAD2),Yeast Yeast
CSB-EP735708PYX Recombinant Pongo abelii Mothers against decapentaplegic homolog 2(SMAD2),Escherichia Coli E.coli
CSB-BP735708PYX Recombinant Pongo abelii Mothers against decapentaplegic homolog 2(SMAD2),Baculovirus Baculovirus
CSB-MP735708PYX Recombinant Pongo abelii Mothers against decapentaplegic homolog 2(SMAD2),Mammalian cell Mammalian cell

SMAD2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Code Product Name Source
CSB-YP884853DIL Recombinant Danio rerio Mothers against decapentaplegic homolog 2(smad2),Yeast Yeast
CSB-EP884853DIL Recombinant Danio rerio Mothers against decapentaplegic homolog 2(smad2),Escherichia Coli E.coli
CSB-BP884853DIL Recombinant Danio rerio Mothers against decapentaplegic homolog 2(smad2),Baculovirus Baculovirus
CSB-MP884853DIL Recombinant Danio rerio Mothers against decapentaplegic homolog 2(smad2),Mammalian cell Mammalian cell

SMAD2 cDNA

SMAD2 cDNA for Bos taurus (Bovine)

Code Product Name Vector Accession NO.
CSB-CL630205BO SMAD2 pUC NM_001046218.1

SMAD2 cDNA for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code Product Name Vector Accession NO.
CSB-CL735708PYX SMAD2 pUC NM_001132904.2

SMAD2 ELISA Kit

SMAD2 ELISA Kit for Homo sapiens (Human)

Code Product Name Sample Types Sensitivity
CSB-E15763h Human Mothers Against Decapentaplegic Homolog 2(SMAD2) ELISA Kit serum, plasma, tissue homogenates, cell lysates 7.8 pg/mL

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