SMAD2

Mothers against decapentaplegic homolog 2 is a protein in humans that is encoded by SMAD2 gene. Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.

The following SMAD2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

SMAD2 Antibodies

SMAD2 Proteins

SMAD2 Antibodies

SMAD2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA021787GA01HU	SMAD2 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA783890	Phospho-SMAD2 (Ser467) Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA084599	Phospho-SMAD2 (Thr220) Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA047751	SMAD2 (Ab-467) Antibody	Human,Mouse,Rat	ELISA,WB,IF
CSB-PA093530	SMAD2 (Ab-220) Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA788461	Phospho-SMAD2 (Ser250) Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA139936	Phospho-SMAD2 (Ser465) Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA594584	SMAD2 (Ab-220) Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA981649	SMAD2 (Ab-465) Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA000675	Phospho-SMAD2 (S467) Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA004106	SMAD2 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA004107	SMAD2 Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA004109	SMAD2 Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA009933	Phospho-SMAD2 (S250) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA009945	Phospho-SMAD2 (S465) Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA009946	Phospho-SMAD2 (T220) Antibody	Human,Mouse,Rat	IHC, IF, ELISA
CSB-PA009952	SMAD2 Antibody	Human,Mouse,Rat	WB, IHC, IF, ELISA
CSB-PA009953	SMAD2 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA080253	SMAD2 Antibody	Human	WB
CSB-PA15557A0Rb	SMAD2 Antibody	Human, Mouse	ELISA, WB, IHC, IF
CSB-PA15557B0Rb	SMAD2 Antibody, HRP conjugated	Human	ELISA
CSB-PA15557C0Rb	SMAD2 Antibody, FITC conjugated	Human
CSB-PA15557D0Rb	SMAD2 Antibody, Biotin conjugated	Human	ELISA
CSB-RA618017A250phHU	Phospho-SMAD2 (S250) Recombinant Monoclonal Antibody	Human	ELISA, WB
CSB-RA618017A255phHU	Phospho-SMAD2 (S255) Recombinant Monoclonal Antibody	Human	ELISA, IF

SMAD2 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Species Reactivity	Application
CSB-PA884853XA01DIL	smad2 Antibody	Danio rerio (Zebrafish) (Brachydanio rerio)	ELISA, WB (ensure identification of antigen)

SMAD2 Proteins

SMAD2 Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP021787RA CSB-EP021787RA CSB-BP021787RA CSB-MP021787RA CSB-EP021787RA-B	Recombinant Rat Mothers against decapentaplegic homolog 2 (Smad2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SMAD2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP618017HU CSB-BP618017HU CSB-MP618017HU CSB-EP618017HU-B	Recombinant Human Mothers against decapentaplegic homolog 2 (SMAD2)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP618017HUa2	Recombinant Human Mothers against decapentaplegic homolog 2 (SMAD2)	E.coli

SMAD2 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP630205BO CSB-EP630205BO CSB-BP630205BO CSB-MP630205BO CSB-EP630205BO-B	Recombinant Bovine Mothers against decapentaplegic homolog 2 (SMAD2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SMAD2 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP733826MO CSB-EP733826MO CSB-BP733826MO CSB-MP733826MO CSB-EP733826MO-B	Recombinant Mouse Mothers against decapentaplegic homolog 2 (Smad2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SMAD2 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

Code	Product Name	Source
CSB-YP735708PYX CSB-EP735708PYX CSB-BP735708PYX CSB-MP735708PYX CSB-EP735708PYX-B	Recombinant Pongo abelii Mothers against decapentaplegic homolog 2 (SMAD2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SMAD2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

Code	Product Name	Source
CSB-YP884853DIL CSB-EP884853DIL CSB-BP884853DIL CSB-MP884853DIL CSB-EP884853DIL-B	Recombinant Danio rerio Mothers against decapentaplegic homolog 2 (smad2)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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