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Mothers against decapentaplegic homolog 2 is a protein in humans that is encoded by SMAD2 gene. Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
The following SMAD2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SMAD2 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA021787GA01HU | SMAD2 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA783890 | Phospho-SMAD2 (Ser467) Antibody |
Human,Mouse,Rat | ELISA,WB |
| CSB-PA084599 | Phospho-SMAD2 (Thr220) Antibody |
Human,Mouse,Rat | ELISA,WB |
| CSB-PA047751 | SMAD2 (Ab-467) Antibody |
Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA093530 | SMAD2 (Ab-220) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA788461 | Phospho-SMAD2 (Ser250) Antibody |
Human,Mouse,Rat | ELISA,WB |
| CSB-PA139936 | Phospho-SMAD2 (Ser465) Antibody |
Human,Mouse,Rat | ELISA,WB |
| CSB-PA594584 | SMAD2 (Ab-220) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA981649 | SMAD2 (Ab-465) Antibody |
Human,Mouse,Rat | ELISA,WB |
| CSB-PA000675 | Phospho-SMAD2 (S467) Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA004106 | SMAD2 Antibody |
Human,Mouse,Rat | WB, ELISA |
| CSB-PA004107 | SMAD2 Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA004109 | SMAD2 Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA009933 | Phospho-SMAD2 (S250) Antibody |
Human,Mouse,Rat | WB, ELISA |
| CSB-PA009945 | Phospho-SMAD2 (S465) Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA009946 | Phospho-SMAD2 (T220) Antibody |
Human,Mouse,Rat | IHC, IF, ELISA |
| CSB-PA009952 | SMAD2 Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA009953 | SMAD2 Antibody |
Human,Mouse,Rat | WB, ELISA |
| CSB-PA080253 | SMAD2 Antibody |
Human | WB |
| CSB-PA15557A0Rb | SMAD2 Antibody |
Human, Mouse | ELISA, WB, IHC, IF |
| CSB-PA15557B0Rb | SMAD2 Antibody, HRP conjugated |
Human | ELISA |
| CSB-PA15557C0Rb | SMAD2 Antibody, FITC conjugated |
Human | |
| CSB-PA15557D0Rb | SMAD2 Antibody, Biotin conjugated |
Human | ELISA |
| CSB-RA618017A250phHU | Phospho-SMAD2 (S250) Recombinant Monoclonal Antibody |
Human | ELISA, WB |
| CSB-RA618017A255phHU | Phospho-SMAD2 (S255) Recombinant Monoclonal Antibody |
Human | ELISA, IF |
SMAD2 Antibodies for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA884853XA01DIL | smad2 Antibody |
Danio rerio (Zebrafish) (Brachydanio rerio) | ELISA, WB (ensure identification of antigen) |
SMAD2 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP021787RA CSB-EP021787RA CSB-BP021787RA CSB-MP021787RA CSB-EP021787RA-B |
Recombinant Rat Mothers against decapentaplegic homolog 2 (Smad2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SMAD2 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP618017HU CSB-BP618017HU CSB-MP618017HU CSB-EP618017HU-B |
Recombinant Human Mothers against decapentaplegic homolog 2 (SMAD2) |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP618017HUa2 | Recombinant Human Mothers against decapentaplegic homolog 2 (SMAD2) |
E.coli |
SMAD2 Proteins for Bos taurus (Bovine)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP630205BO CSB-EP630205BO CSB-BP630205BO CSB-MP630205BO CSB-EP630205BO-B |
Recombinant Bovine Mothers against decapentaplegic homolog 2 (SMAD2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SMAD2 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP733826MO CSB-EP733826MO CSB-BP733826MO CSB-MP733826MO CSB-EP733826MO-B |
Recombinant Mouse Mothers against decapentaplegic homolog 2 (Smad2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SMAD2 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP735708PYX CSB-EP735708PYX CSB-BP735708PYX CSB-MP735708PYX CSB-EP735708PYX-B |
Recombinant Pongo abelii Mothers against decapentaplegic homolog 2 (SMAD2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SMAD2 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP884853DIL CSB-EP884853DIL CSB-BP884853DIL CSB-MP884853DIL CSB-EP884853DIL-B |
Recombinant Danio rerio Mothers against decapentaplegic homolog 2 (smad2) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
