STAT3 (Signal Transducer and Activator of Transcription 3) is a signal transduction and transcription activation factor. It participates in cellular signaling pathways and regulates gene transcription within the cell nucleus. When cells are exposed to specific signaling cues such as cytokines, growth factors, or activated receptors, STAT3 becomes phosphorylated and forms dimers or multimers. These phosphorylated STAT3 complexes translocate to the cell nucleus and bind to specific promoter regions of target genes, thereby modulating the transcription levels of these genes. The activation of STAT3 is closely associated with numerous biological processes, including cell proliferation, cell survival, and immune responses. Research on STAT3 contributes to a deeper understanding of cellular signal transduction and gene regulation mechanisms, offering potential novel therapeutic strategies for related diseases.
● STAT3 Recombinant Monoclonal Antibody CSB-RA022812MA1HU
Validated Data
The Binding Activity of Human STAT3 with Anti-STAT3 Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human STAT3 (CSB-BP022812HU(A4)j7) at 2 μg/mL can bind Anti-STAT3 recombinant antibody , the EC50 is 41.31-75.59 ng/mL
The following STAT3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
STAT3 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA022812GA01HU | STAT3 Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA954939 | Phospho-STAT3 (Tyr705) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA699573 | Phospho-STAT3 (Ser727) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA088158 | STAT3 (Ab-727) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA586999 | STAT3 (Ab-705) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA000621 | Phospho-STAT3 (S727) Antibody |
Human,Mouse,Rat,Monkey | WB, IHC, IP, ELISA |
CSB-PA000622 | Phospho-STAT3 (Y705) Antibody |
Human, Mouse, Rat | WB, IHC, IP, ELISA |
CSB-PA004173 | STAT3 Antibody |
Human,Mouse,Rat | WB, IHC, ELISA |
CSB-PA004174 | STAT3 Antibody |
Human,Mouse,Rat | WB, IHC, IF, ELISA |
CSB-PA050164 | STAT3 Antibody |
Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
CSB-PA080245 | STAT3 Antibody |
Human | WB, IHC |
CSB-PA022812LA01HU | STAT3 Antibody |
Human | ELISA, IHC, IF, IP |
CSB-PA022812LB01HU | STAT3 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA022812LC01HU | STAT3 Antibody, FITC conjugated |
Human | |
CSB-PA022812LD01HU | STAT3 Antibody, Biotin conjugated |
Human | ELISA |
CSB-RA022812A727phHU | Phospho-STAT3 (S727) Recombinant Monoclonal Antibody |
Human | ELISA, WB, IHC, IP |
CSB-RA022812A705phHU | Phospho-STAT3 (Tyr705) Recombinant Monoclonal Antibody |
Human | ELISA, WB, IHC |
CSB-RA546821A0HU | STAT3 Recombinant Monoclonal Antibody |
Human | ELISA, FC |
CSB-RA229700A0HU | STAT3 Recombinant Monoclonal Antibody |
Human | ELISA, WB, IHC |
CSB-RA188270A0HU | STAT3 Recombinant Monoclonal Antibody |
Human | ELISA, IHC |
CSB-RA022812MA1HU | STAT3 Recombinant Monoclonal Antibody |
Human | ELISA |
STAT3 Antibodies for Mus musculus (Mouse)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA022812XA01MO | Stat3 Antibody |
Mus musculus (Mouse) | ELISA, WB (ensure identification of antigen) |
STAT3 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP022812HU CSB-BP022812HU CSB-MP022812HU CSB-EP022812HU-B |
Recombinant Human Signal transducer and activator of transcription 3(STAT3),partial |
Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP022812HU | Recombinant Human Signal transducer and activator of transcription 3(STAT3),partial |
E.coli |
CSB-YP022812HU(A4) | Recombinant Human Signal transducer and activator of transcription 3(STAT3) |
Yeast |
CSB-EP022812HU(A4) | Recombinant Human Signal transducer and activator of transcription 3(STAT3) |
E.coli |
CSB-EP022812HU(A4)-B | Recombinant Human Signal transducer and activator of transcription 3(STAT3),Biotinylated |
E.coli |
CSB-EP022812HU2 | Recombinant Human Signal transducer and activator of transcription 3(STAT3),partial |
E.coli |
STAT3 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP022812MO CSB-EP022812MO CSB-BP022812MO CSB-MP022812MO CSB-EP022812MO-B |
Recombinant Mouse Signal transducer and activator of transcription 3(Stat3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
STAT3 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP022812RA CSB-EP022812RA CSB-BP022812RA CSB-MP022812RA CSB-EP022812RA-B |
Recombinant Rat Signal transducer and activator of transcription 3(Stat3) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
STAT3 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP022812BO CSB-EP022812BO CSB-BP022812BO CSB-MP022812BO CSB-EP022812BO-B |
Recombinant Bovine Signal transducer and activator of transcription 3(STAT3) ,partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
STAT3 Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP624331PI CSB-EP624331PI CSB-BP624331PI CSB-MP624331PI CSB-EP624331PI-B |
Recombinant Pig Signal transducer and activator of transcription 3(STAT3) ,partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
STAT3 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP728573CH CSB-EP728573CH CSB-BP728573CH CSB-MP728573CH CSB-EP728573CH-B |
Recombinant Chicken Signal transducer and activator of transcription 3(STAT3) ,partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |