TYR

The gene TYR encodes the enzyme tyrosinase, also known as tyrosinase-related protein 1 (TRP1). This enzyme plays a crucial role in melanin synthesis, which is essential for skin pigmentation and protection against UV radiation. Tyrosinase catalyzes the conversion of tyrosine to dopa, the first step in melanin production. Dysregulation of TYR is associated with oculocutaneous albinism, a genetic disorder characterized by reduced melanin production leading to light-colored skin, hair, and eyes. Targeted therapies for TYR-related diseases are being developed, focusing on tyrosinase inhibitors to restore normal melanin synthesis and treat related conditions.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TYR Recombinant Monoclonal Antibody (CSB-RA567167A0HU)

Validated Data

Immunofluorescence staining of MCF7 Cells with CSB-RA567167A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

Human Tyrosinase(TYR) ELISA kit (CSB-EL025394HU)

Validated Data

Code: CSB-EL025394HU

Size: 96T,5×96T,10×96T

Sensitivity: 3.9 pg/mL

Detection Range: 15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following TYR reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TYR Antibodies

TYR Proteins

TYR ELISA Kits

TYR Antibodies

TYR Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA025394LA01HU	TYR Antibody	Human	ELISA, IHC, IF
CSB-PA025394LB01HU	TYR Antibody, HRP conjugated	Human	ELISA
CSB-PA025394LC01HU	TYR Antibody, FITC conjugated	Human
CSB-PA025394LD01HU	TYR Antibody, Biotin conjugated	Human	ELISA
CSB-PA589649	Tyrosinase Antibody	Human	WB
CSB-PA004353	TYR Antibody	Human,Monkey	WB, ELISA
CSB-PA112776	TYR Antibody	Human,Mouse	ELISA,WB
CSB-PA986893	TYR Antibody	Human,Mouse	ELISA,WB,IHC
CSB-RA567167A0HU	TYR Recombinant Monoclonal Antibody	Human	ELISA, IF

TYR Proteins

TYR Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP025394MO1 CSB-EP025394MO1 CSB-BP025394MO1 CSB-MP025394MO1 CSB-EP025394MO1-B	Recombinant Mouse Tyrosinase (Tyr), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF025394MO	Recombinant Mouse Tyrosinase (Tyr)	in vitro E.coli expression system

TYR Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-EP025394HU	Recombinant Human Tyrosinase (TYR), partial	E.coli
CSB-YP025394HU	Recombinant Human Tyrosinase (TYR), partial	Yeast
CSB-BP025394HU CSB-MP025394HU CSB-EP025394HU-B	Recombinant Human Tyrosinase (TYR), partial	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-BP025394HU2	Recombinant Human Tyrosinase (TYR), partial	Baculovirus

TYR Proteins for Felis catus (Cat) (Felis silvestris catus)

Code	Product Name	Source
CSB-YP025394CA CSB-EP025394CA CSB-BP025394CA CSB-MP025394CA CSB-EP025394CA-B	Recombinant Cat Tyrosinase (TYR)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TYR Proteins for Pelodiscus sinensis (Chinese softshell turtle) (Trionyx sinensis)

Code	Product Name	Source
CSB-YP025394PEL CSB-EP025394PEL CSB-BP025394PEL CSB-MP025394PEL CSB-EP025394PEL-B	Recombinant Pelodiscus sinensis Tyrosinase (TYR)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TYR Proteins for Coturnix japonica (Japanese quail) (Coturnix coturnix japonica)

Code	Product Name	Source
CSB-YP600102DXJ CSB-EP600102DXJ CSB-BP600102DXJ CSB-MP600102DXJ CSB-EP600102DXJ-B	Recombinant Coturnix coturnix japonica Tyrosinase (TYR)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TYR Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP818647BO CSB-EP818647BO CSB-BP818647BO CSB-MP818647BO CSB-EP818647BO-B	Recombinant Bovine Tyrosinase (TYR), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TYR Proteins for Gorilla gorilla gorilla (Western lowland gorilla)

Code	Product Name	Source
CSB-YP860196GGZ CSB-EP860196GGZ CSB-BP860196GGZ CSB-MP860196GGZ CSB-EP860196GGZ-B	Recombinant Gorilla gorilla gorilla Tyrosinase (TYR), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TYR Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-CF025394CH	Recombinant Chicken Tyrosinase (TYR)	in vitro E.coli expression system
CSB-YP025394CH1 CSB-EP025394CH1 CSB-BP025394CH1 CSB-MP025394CH1 CSB-EP025394CH1-B	Recombinant Chicken Tyrosinase (TYR), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TYR Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-CF025394DO	Recombinant Dog Tyrosinase (TYR)	in vitro E.coli expression system
CSB-YP025394DO1 CSB-EP025394DO1 CSB-BP025394DO1 CSB-MP025394DO1 CSB-EP025394DO1-B	Recombinant Dog Tyrosinase (TYR), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TYR Proteins for Pelophylax nigromaculatus (Black-spotted frog) (Rana nigromaculata)

Code	Product Name	Source
CSB-CF025394PEM	Recombinant Pelophylax nigromaculatus Tyrosinase (TYR)	in vitro E.coli expression system
CSB-YP025394PEM1 CSB-EP025394PEM1 CSB-BP025394PEM1 CSB-MP025394PEM1 CSB-EP025394PEM1-B	Recombinant Pelophylax nigromaculatus Tyrosinase (TYR), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

TYR Proteins for Oryzias latipes (Japanese rice fish) (Japanese killifish)

Code	Product Name	Source
CSB-CF025394OFH	Recombinant Oryzias latipes Tyrosinase (tyr)	in vitro E.coli expression system
CSB-YP025394OFH1 CSB-EP025394OFH1 CSB-BP025394OFH1 CSB-MP025394OFH1 CSB-EP025394OFH1-B	Recombinant Oryzias latipes Tyrosinase (tyr), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli