Protein Wnt-5ais a protein in humans that is encoded by WNT5A gene. Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor. Mediates motility of melanoma cells.

WNT5A Antibodies

WNT5A Antibodies for Homo sapiens (Human)

WNT5A Proteins

WNT5A Proteins for Homo sapiens (Human)

WNT5A Proteins for Mus musculus (Mouse)

WNT5A Proteins for Xenopus laevis (African clawed frog)

WNT5A Proteins for Anser caerulescens (Snow goose) (Chen caerulescens)

WNT5A Proteins for Meleagris gallopavo (Wild turkey)

WNT5A Proteins for Pleurodeles waltl (Iberian ribbed newt)

WNT5A Proteins for Oryctolagus cuniculus (Rabbit)

WNT5A Proteins for Rattus norvegicus (Rat)


WNT5A ELISA Kit for Homo sapiens (Human)

WNT5A ELISA Kit for Mus musculus (Mouse)


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