Recombinant Mouse Interleukin-13 protein(Il13) (Active)

Code CSB-AP003371MO
Product Type Interleukin
Size Pls inquiry other sizesPurchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P20109
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias IL-13
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 4 ng/ml, corresponding to a specific activity of >2.5x105 IU/mg.
Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence M+PVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F
Research Area Immunology
Source E.coli
Gene Names Il13
Expression Region 22-131aa
Tag Info Tag-Free
Mol. Weight 12.3 kDa
Protein Description Full Length of Mature Protein
PubMed ID 2521353
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Function Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses (By similarity). Positively regulates IL31RA expression in macrophages
Subcellular Location Secreted
Protein Families IL-4/IL-13 family
Database Links

KEGG: mmu:16163

STRING: 10090.ENSMUSP00000020650

UniGene: Mm.1284

Pathway Jak-STAT signaling pathway
Fc epsilon RI signaling pathway
IL-17 signaling pathway
Th1 and Th2 cell differentiation

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