Recombinant Mouse Interleukin-13(Il13)

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Code CSB-AP004751MO
Product Type Interleukin
Size US$195Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P20109
Lead Time 5-10 business days
Storage Buffer Lyophilized from a 0.2 μm filtered 1xPBS, pH 7.4
Alias Interleukin-13; IL-13; T-Cell Activation Protein P600; Il13; Il-13
Species Mus musculus (Mouse)
Biological_Activity The ED50 as determined in a cell proliferation assay using TF?1 human erythroleukemic cells is less than 20 ng/ml.
Purity Greater than 95% as determined by SDS-PAGE.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence PVPRSVSLPLTLKELIEELSNITQDQTPLCNGSMVWSVDLAAGGFCVALDSLTNISNCNAIYRTQRILHGLCNRKAPTTVSSLPDTKIEVAHFITKLLSYTKQLFRHGPF
Research Area Immunology
Source Mammalian cell
Gene Names Il13
Expression Region 22-131aa
Tag Info C-terminal 6xHis-tagged
Mol. Weight 13.1 kDa
Protein Description Full Length of Mature Protein
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Function Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses (By similarity). Positively regulates IL31RA expression in macrophages
Subcellular Location Secreted
Protein Families IL-4/IL-13 family
Database Links

KEGG: mmu:16163

STRING: 10090.ENSMUSP00000020650

UniGene: Mm.1284

Pathway Jak-STAT signaling pathway
Fc epsilon RI signaling pathway
IL-17 signaling pathway
Th1 and Th2 cell differentiation

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