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Recombinant Macaca fascicularis Cadherin-1 (CDH1), partial (Active)

Recombinant Macaca fascicularis Cadherin-1 (CDH1), partial (Active)

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Code	CSB-MP5601MOV
Abbreviation	Recombinant Cynomolgus monkey CDH1 protein, partial (Active)
MSDS	MSDS Datasheet
Size	$102
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Image	(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel. Activity Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus CDH1 at 2 μg/ml can bind Anti-CDH1 recombinant antibody (CSB-RA005034MA2HU). The EC₅₀ is 2.256-2.744 ng/mL. Biological Activity Assay The purity of CDH1 was greater than 95% as determined by SEC-HPLC
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Product Details
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Product Details

Purity

≥ 95% as determined by SDS-PAGE.
≥ 95% as determined by SEC-HPLC.

Activity

Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus CDH1 at 2 μg/mL can bind Anti-CDH1 recombinant antibody (CSB-RA005034MA2HU). The EC50 is 2.256-2.744 ng/mL.

Target Names

CDH1

Uniprot No.

A0A2K5V299

Alternative Names

Cadherin-1; Epithelial cadherin

Species

Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Source

Mammalian cell

Expression Region

155-708aa

Target Protein Sequence

DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRENIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPVFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYSILSQDPELPDKNMFTINKNTGVISVVTTGLDRESFPMYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPVFNPTTYKGQVPENQANFVITTLKVTDADAPNTPAWEAVYTILNDNDGQFVVTTNPVTNDGILKTAKGLDFEAKQQYILHVAVTNVAPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAREPDTFMEQKITYRIWRDAANWLEINPDTGAISTRAELDREDVEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPESRNLFFCERNPKPQVINIIDADLPPNTSPFTAELMHGASANWTIEYNDPTQESIILKPKIALEVGDYKINLKLMDNQKKDQVTTLEVSVCDCEGAAGICKKAPLVEAGMQIP

Mol. Weight

61.9 kDa

Protein Length

Partial

Tag Info

C-terminal 10xHis-tagged

Form

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer

Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

3-7 business days

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet & COA

Please contact us to get it.

Description

Cadherin-1 mediates calcium-dependent homophilic cell–cell adhesion in epithelial tissues, and its dysregulation is implicated in tumor invasion and metastasis, making it a critical target for cancer biology studies. This recombinant cynomolgus CDH1 fragment spans residues 155–708, covering the extracellular cadherin repeats essential for adhesive function, and demonstrates specific antibody binding with an EC50 of 2.256–2.744 ng/mL in functional ELISA, confirming proper folding and epitope accessibility. The quantified binding activity supports its use in antibody development and validation workflows, where dose-dependent recognition is required to assess candidate therapeutic or diagnostic reagents. With purity exceeding 95% by SDS-PAGE and endotoxin levels below 1.0 EU/μg, this protein meets the quality thresholds commonly required for cell adhesion assays, migration and invasion studies, and tumor metastasis research involving epithelial-to-mesenchymal transition models.