AGT

AGT, or Angiotensinogen, is a key component of the renin-angiotensin-aldosterone system (RAAS), encoded by the AGT gene, and synthesized in the liver. It is converted into angiotensin I by renin and then into angiotensin II by angiotensin-converting enzyme (ACE), participating in the regulation of blood pressure and electrolyte balance. Abnormal AGT expression is related to hypertension and preeclampsia, and RNAi therapy targeting AGT, such as ALN-AGT, may revolutionize hypertension treatment by reducing drug administration frequency and improving patient compliance.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

AGT Recombinant Monoclonal Antibody (CSB-RA263831A0HU)

Validated Data

IHC image of CSB-RA263831A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

Human angiotensinogen (aGT) ELISA Kit (CSB-E08564h)

Validated Data

Code: CSB-E08564h

Size: 96T,5×96T,10×96T

Sensitivity: 19.5 pg/mL

Detection Range: 78 pg/mL-5000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following AGT reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

AGT Antibodies

AGT Proteins

AGT ELISA Kits

AGT Antibodies

AGT Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA001463GA01HU	AGT Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA001463ESR1HU	AGT Antibody	Human	ELISA, IHC, IF
CSB-PA001463ESR2HU	AGT Antibody	Human, Mouse	ELISA, WB, IHC, IF
CSB-PA10079A0Rb	AGT Antibody	Human	ELISA, WB, IHC, IF
CSB-PA982509	AGT Antibody	Human	ELISA,WB
CSB-PA281661	AGT Antibody	Human	ELISA,WB
CSB-PA959270	AGT Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA446811	AGT Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA693559	AGT Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA090852	AGT Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA173097	AGT Antibody	Human,Mouse,Rat	ELISA
CSB-PA001463EA01HU	AGT Antibody	Human, Rat	ELISA, WB, IHC
CSB-RA263831A0HU	AGT Recombinant Monoclonal Antibody	Human	ELISA, IHC

AGT Antibodies for Enterobacteria phage T4 (Bacteriophage T4)

Code	Product Name	Species Reactivity	Application
CSB-PA356278XA01EDZ	agt Antibody	Enterobacteria phage T4 (Bacteriophage T4)	ELISA, WB (ensure identification of antigen)

AGT Proteins

AGT Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP001463CH CSB-EP001463CH CSB-BP001463CH CSB-MP001463CH CSB-EP001463CH-B	Recombinant Chicken Angiotensinogen (AGT)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

AGT Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP001463MO CSB-EP001463MO CSB-BP001463MO CSB-MP001463MO CSB-EP001463MO-B	Recombinant Mouse Angiotensinogen (Agt)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

AGT Proteins for Ovis aries (Sheep)

Code	Product Name	Source
CSB-YP001463SH CSB-EP001463SH CSB-BP001463SH CSB-MP001463SH CSB-EP001463SH-B	Recombinant Sheep Angiotensinogen (AGT)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

AGT Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP001463HU CSB-BP001463HU CSB-MP001463HU CSB-EP001463HU-B	Recombinant Human Angiotensinogen (AGT)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP001463HU1	Recombinant Human Angiotensinogen (AGT), partial	E.coli

AGT Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP001463RA CSB-EP001463RA CSB-BP001463RA CSB-MP001463RA CSB-EP001463RA-B	Recombinant Rat Angiotensinogen (Agt)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

AGT Proteins for Equus caballus (Horse)

Code	Product Name	Source
CSB-YP001463HO CSB-EP001463HO CSB-BP001463HO CSB-MP001463HO CSB-EP001463HO-B	Recombinant Horse Angiotensinogen (AGT)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

AGT Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP001463BO CSB-EP001463BO CSB-BP001463BO CSB-MP001463BO CSB-EP001463BO-B	Recombinant Bovine Angiotensinogen (AGT)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

AGT Proteins for Coturnix japonica (Japanese quail) (Coturnix coturnix japonica)

Code	Product Name	Source
CSB-YP001463DXJ CSB-EP001463DXJ CSB-BP001463DXJ CSB-MP001463DXJ CSB-EP001463DXJ-B	Recombinant Coturnix coturnix japonica Angiotensinogen (AGT)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

AGT Proteins for Enterobacteria phage T4 (Bacteriophage T4)

Code	Product Name	Source
CSB-YP356278EDZ CSB-BP356278EDZ CSB-MP356278EDZ CSB-EP356278EDZ-B	Recombinant Enterobacteria phage T4 DNA alpha-glucosyltransferase (agt)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

AGT Proteins for Pan troglodytes (Chimpanzee)

Code	Product Name	Source
CSB-YP861947EQV CSB-EP861947EQV CSB-BP861947EQV CSB-MP861947EQV CSB-EP861947EQV-B	Recombinant Pan troglodytes Angiotensinogen (AGT)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

AGT Proteins for Gorilla gorilla gorilla (Western lowland gorilla)

Code	Product Name	Source
CSB-YP863905GGZ CSB-EP863905GGZ CSB-BP863905GGZ CSB-MP863905GGZ CSB-EP863905GGZ-B	Recombinant Gorilla gorilla gorilla Angiotensinogen (AGT)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

AGT Proteins for Callithrix jacchus (White-tufted-ear marmoset)

Code	Product Name	Source
CSB-YP871317CYL CSB-EP871317CYL CSB-BP871317CYL CSB-MP871317CYL CSB-EP871317CYL-B	Recombinant Callithrix jacchus Angiotensinogen (AGT)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli